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The Effect of Mental Fatigue on Lower Limb Functional Performance Tests and Brain Activity in a Healthy Population

The Influence of Acute Mental Fatigue on Functional Performance Tests of the Lower Limb and Brain Activity in a Healthy Population

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03643406
Enrollment
13
Registered
2018-08-22
Start date
2018-10-19
Completion date
2019-07-17
Last updated
2019-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain Activity, EEG, Functional Performance, Mental Fatigue, Return to Sport

Brief summary

Objective of the study The main objectives of this project are: 1. To assess the influence of mental fatigue on a return-to-play test battery in healthy population 2. To assess the influence of mental fatigue on brain functioning during a balance and reaction time task in healthy population In a later stage, these experiments could be carried out in a clinical context (e.g. in an ankle sprain population). The researchers will use a randomized, placebo controlled, counter-balanced, cross-over design. Thirteen healthy subjects will visit the lab 3 times. On the first visit (familiarisation trial), the investigators will collect the participants' characteristics. The participants will also be familiarized to the procedures and materials of the experiment during this first visit. The second and third visit contain the experimental setup and will proceed as follows: first, the participants will fill in a mental fatigue scale (M-VAS) and motivation scale. Next, the subjects will carry out a functional test battery (hop test, vertical jump test, Y-balance test, and a balance reaction-time test). Session rate of perceived exertion (RPE) is measured to indicate how fatigued the participants feel because of the test battery; also, M-VAS is collected once more. Then, a short cognitive task (Flanker task) is followed by either a long intensive cognitive task (90 minutes Stroop task) or control task (90 minutes documentary). Afterwards, participants have to carry out the Flanker task, fill in M-VAS (2x), perform the same test battery, fill in session RPE and one final fatigue scale (Nasa TLX). Heart frequency and EEG will be measured continuously during the trials.

Interventions

OTHERMental Fatigue

modified stroop task

OTHERControl

documentary

Sponsors

Vrije Universiteit Brussel
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy (No neurological/cardiorespiratory/psychological disorders) * Male and female * No medication * Non-smoker * Between 18 and 35 years old

Exclusion criteria

* Back and/or lower extremity injuries during the past 6 months * Bone/joint abnormalities * Dizziness, history of loss of consciousness, any inner ear disorders * Nervous system disorders or dysfunctions * Uncorrected eye disorders/dysfunctions * Illness * Use of medication or any kind of drugs * Use of alcohol, caffeine and heavy efforts 24 hours before each trial * Not eating the same meal the night before and the morning of each trial

Design outcomes

Primary

MeasureTime frameDescription
EEG power spectrum analysisChange in EEG power spectrum: from baseline and 120 minutes after baseline (immediately after the flanker task)Brain activity during the Y-balance test, balance-reaction time test and flanker task will be registered at baseline and immediately after the flanker task
Vertical jump testChange in vertical jump height performance: from baseline and 120 minutes after baseline (immediately after the flanker task)Vertical jump height performance
Y-balance testChange in Y-balance performance: from baseline and 120 minutes after baseline (immediately after the flanker task)Balance and reach performance; participants have to maintain their balance while reaching as far as possible along 3 different directions.
Balance-reaction time testChange in balance and reaction time performance: from baseline and 120 minutes after baseline (immediately after the flanker task)Balance and reaction time performance; participants have to maintain their balance while reacting as fast as possible in 3 different directions.
Single-leg hop testChange in single-leg hop test for distance performance: from baseline and 120 minutes after baseline (immediately after the flanker task)Single-leg hop test for distance performance

Secondary

MeasureTime frameDescription
Flanker taskChange in flanker task: at baseline and 90 minutes after baseline (immediately after the mental fatiguing task)Objective measure of mental fatigue; reaction time and accuracy give an objective indication of mental fatigue
90-minute stroop taskChange in reaction time and accuracy will be assessed with a 90-min cognitive task; Reaction Time and Accuracy during the 90-min task will be reported as mean reaction time and accuracy during 8 blocks of 11min15sec90 minutes mental fatiguing task; reaction time and accuracy give an objective indication of mental fatigue
Mental fatigue Visual Analogue Scale (M-VAS)Change in M-VAS: at baseline, 20 min after baseline (immediately after the first test battery), 120 min after baseline (immediately after the second flanker task) and 135 min after baseline (immediately after the final test battery)Subjective measure of mental fatigue (0-10cm; 0 = no mental fatigue; 10 = maximal mental fatigue)

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026