Multiple Sclerosis, Radiologically Isolated Syndrome (RIS)
Conditions
Brief summary
This study aims to investigate the prevalence of subclinical oculomotor disorders in a population of patients with radiologically isolated syndrome.
Interventions
OTHERNeurological consultation
study of horizontal, vertical, reflex and voluntary saccades, and of horizontal and vertical ocular pursuit by a BrainTracker eye-oculography system
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* The patient must have given his informed consent and signed the consent form. * The patient must be affiliated or beneficiary of a health insurance plan. * The patient is at least 18 years old (≥) and under 50 years old (≤). * Patients with radiologically isolated syndrome according to the criteria of Okuda et al. (2009) * Diagnosis of a radiologically isolated syndrome confirmed by the national expert center of Nice for less than 3 years.
Exclusion criteria
* The subject participates in another study. * The subject is in an exclusion period determined by a previous study. * The subject is under guardianship, curatorship or safeguard of justice. * The patient is pregnant or breastfeeding * The subject refuses to sign the consent. * It is not possible to give the subject informed information. * Patient presenting a pathological neurological examination. * Patient with visual acuity less than 5/10 or with ocular instability
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Evaluation of the occurrence of oculomotor disorders | Day 0 | using a video-oculographic recording system |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| To establish the prevalence of each of the different types of oculomotor abnormalities that constitute the oculomotor disorder | Day 0 | number |
| To identify a correlation between oculomotor disorders and MRI abnormalities. | Day 0 | — |
| To identify a correlation between oculomotor disorders and the cognitive impairment test (Symbol Digit Modalities Test) | Day 0 | — |
Countries
France
Outcome results
None listed