Chronic Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome, Premature Ejaculation
Conditions
Keywords
Prostate inflammation, CPS/CPPS, Prostatitis, Proxelan
Brief summary
The purpose of the study is to determinate the antinflammatory effects of the Proxelan on a cohort of patients affected by prostatitis'like symptoms and clinical evidence of abacterical prostatistis, trough a significative improvements of pain symptoms according to the NIH-CPSI questionnaire items, spermatozoa motility/concentration variations and the semen cytokines level decrease.
Interventions
DRUGProxelan
Administration of one suppository of proxelan once a day for 30 days
Sponsors
University of Pisa
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
\- prostatitis like symptoms for at least three months
Exclusion criteria
* significant post-voidal residual volume * Meares and Stamey test suggestive for bacterial infection * neoplasms, * urinary stones, * antibiotic therapy in the previous three months, * irritable bowel syndrome, * previous radiotherapic or chemiotherapic treatment, * urethral stenosis, * neurogenic bladder * previous prostatic surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| National Institutes of Health - Chronic Prostatitis Symptom (NIH-CPS) questionnaires score | 30 days | Evaluation of pain symptoms trough NIH-CPS questionnaires' pain items (0-6). Values from 0 to 3 normal/slight symptoms; Values from 3 to 6 moderate symptoms; Values over 6 severe symptoms. |
Countries
Italy
Outcome results
None listed