Diabetes
Conditions
Brief summary
This study is to evaluate the glycemic variation using Continuous Glucose Monitoring System in patients in the intensive care unit, find out the occult hypoglycemia, and investigate the relationship between glycemic variation, especially the incidence of hypoglycemia and prognosis of patients. Meanwhile, the inflammatory factors were measured and the relationship between inflammatory factors and glycemic variation.
Interventions
DIAGNOSTIC_TESTContinuous Glucose Monitoring System
Continuous Glucose Monitoring System for 72 hours
Sponsors
Nanjing First Hospital, Nanjing Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. Patients with history of diabetes; 2. Patients without history of diabetes, but their random blood glucose≧7.8mmol/L or fast blood glucose≧5 mmol/L; 3. The patients hospitalized in care unit (ICU or CCU) for more than 48 hours.
Exclusion criteria
1. Patient had history of mental illness; 2. Patient was not suitable for using the CGMS; 3. blood glucose \> 22.2 mmol/L at admission.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 28 day prognosis | 0-28 days | Case-fatality at 28 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mean amplitude of glycemic excursion every 24 h | 1-4 days | Mean amplitude of glycemic excursion every 24 h assessed by CGM |
| Incidence of hypoglycemia | 1-4 days | Incidence of hypoglycemia |
| Acute Physiology and Chronic Health Evaluation II score | 0-28 days | Acute Physiology and Chronic Health Evaluation II score |
| Global registry of acute coronary events risk score | 0-28 days | Global registry of acute coronary events risk score |
| Twenty-four-hour mean blood glucose | 1-4 days | Twenty-four-hour mean blood glucose assessed by CGM |
Contacts
Primary ContactHuiqin Li, MD
Outcome results
None listed