Adolescent Behavior, Opioid Use, Substance Abuse Disorder, Traumatic Injury
Conditions
Brief summary
Currently, 1 in 8 adolescents continue to receive prescription opioids a year or more after injury. By longitudinally surveying patients, we can identify risk factors and pathways to nonmedical opioid use. Furthermore, by assessing whether pain management and mental health treatment after injury moderates sustained opioid use and prescription opioid misuse, we can create targeted interventions to reduce future nonmedical opioid use in adolescents.
Detailed description
This is a prospective cohort study that will follow participants for 2 years and administer surveys to adolescents both traumatically injured and uninjured on prescription opioid usage, substance use, utilization of pain management and mental health services, and mental and physical health condition conditions.
Interventions
None listed
Sponsors
Indiana University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
12 Years to 20 Years
Healthy volunteers
Yes
Inclusion criteria
* Patient is 12-20 years of age * Adolescent admitted for trauma OR adolescent with no recent trauma * English speaking * Consent can be obtained from a parent or guardian
Exclusion criteria
\- Patients with severe brain injuries or other injuries that prevent survey participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prospectively determine drivers of sustained opioid use and prescription opioid misuse. | 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Identify patient-reported factors for sustained prescription opioid use, including chronic pain and mental health conditions such as PTSD, depression, anxiety, and sleep disorders. | 2 years |
| Assess behavioral, social, and clinical predictors of prescription opioid misuse and nonmedical opioid use by longitudinally surveying injured adolescents. | 2 years |
| Qualitatively determine patients' motives for continued opioid therapy, prescription opioid misuse, and nonmedical opioid use by interviewing injured adolescents. | 2 years |
| Analyze genetic information, obtained via saliva sample and the company 23andMe, from each participant to determine if some people are more likely to use more pain medication than others or respond better to certain pain medications. | 2 years |
Countries
United States
Outcome results
None listed