Allergic Conjunctivitis, Allergic Rhinitis, Asthma
Conditions
Keywords
asthma, environmental intervention, allergies, air purifier
Brief summary
Exposure to airborne allergens and pollutants is linked to symptom severity of allergies, asthma and other respiratory problems. In this study an air purifier using photo-electrochemical oxidation technology (PECO) will be used in the home environment of study participants. The investigator will assess the reduction of symptoms from allergic rhinitis/conjunctivitis and asthma.
Detailed description
The purpose of this study is to assess the efficacy of the portable PECO air purifier in reducing symptoms from allergic rhinitis and asthma. Using a randomized, double blinded placebo, controlled trial we will be then able to assess if there are any changes after the use of the PECO air purifier after completing an initial baseline survey & comparing to the exit survey. This is a double-blind study, which means that neither the participant nor the investigator knows which device is being used until after the trial is over.
Interventions
OTHERActive air purifier in respiratory allergies/asthma
Continuous use of air purifier to improve allergies and asthma control
OTHERSham air purifier
control arm
Sponsors
Molekule
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
1. Chronic allergic rhinitis and/or conjunctivitis by history 2. History of adult asthma requiring medications now or in the past 3. Age ≥18 4. CARAT score less than 24
Exclusion criteria
1. Participant is \<18 years-old 2. Use of systemic corticosteroids within 14 days of study initiation 3. Treatment with biologic agents or allergen immunotherapy 4. Treatment with other immunomodulators (cyclosporine, azathioprine, hydroxychloroquine, etc) 5. Sensitive to fan sound or blue/purple light at night time
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Control of Allergic Rhinitis and Asthma Test (CARAT) score | 4 weeks | CARAT will measure the change in control scores of respiratory allergies and asthma. Scale 0 (Worse control of allergy and asthma) to 30 (Best control of allergy and asthma). The higher score the better control of allergy and asthma. There are 10 individual questions, scoring from 0-3. |
Countries
United States
Outcome results
None listed