Bacterial Infections, Bone and Joint Infection, EPIDEMIOLOGY
Conditions
Brief summary
This study concerns patients having had an infection on their prosthesis (hip, knee,..) and for whom a 2-step exchange of prosthesis has been done. A 2-step exchange consists in explantation of the prosthesis and implementation of a spacer at the first stage, and reimplantation of a new prosthesis in a second stage. Patients with late prosthetic joint infection are at risk for superinfection at the time of reimplantation. The aim is to determine the microbiological epidemiology in patients experiencing failure following reimplantation to establish, based on the drug susceptibilities, which cement could be the most active.
Interventions
OTHERfailure after reimplantation
description of cinical and microbiological failure
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Inclusion criteria
* patients with prosthetic joint infection having had a 2-step exchange at least from the reimplantation, between 2013 and 2015.
Exclusion criteria
\-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| rate of treatment failure | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption) | Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| rate of bacteria involved in microbiological failure | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption) | description of microbiological failure : bacteria responsible of microbiological failure |
| rate of clinical failure | Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption) | description of clinical failure |
Outcome results
None listed