Quality of Life
Conditions
Keywords
Gastric cancer, Quality of life
Brief summary
The jejunum of the input segment is properly ligated with double line 7 at 3-5cm from the anastomotic site, and the jejunum of the output segment is extended to 30cm
Detailed description
The T1-4a N0-3 M0 gastric adenocarcinoma patients were used to evaluate whether the quality of life after modified BII+Braun digestive tract reconstruction was superior to the traditional BII+Braun digestive tract reconstruction
Interventions
PROCEDUREmodified BII+Braun
modified BII+Braun digestive tract reconstruction
Sponsors
Xue Yingwei
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* 18\<age\<75 * Gastric lesions were diagnosed as gastric adenocarcinoma by endoscopic biopsy * The preoperative clinical stage is T1-4a,N0-3,M0(According to AJCC- 7th TNM tumor stage) * It is expected that the results of R0 surgery can be obtained by performing distal gastrectomy and D2 lymph node dissection * Preoperative ECOG performance status score 0/1 * Nutrition risk screening（NRS2002） * Preoperative ASA score I-III * Patient informed consent
Exclusion criteria
* Pregnancy or breastfeeding women * Severe mental illness * History of upper abdominal surgery * History of gastric surgery (including ESD/EMR for gastric cancer) * 3 years of history of other malignant diseases； * Gastric cancer patients who have undergone neoadjuvant treatment or recommend neoadjuvant treatment * A history of unstable angina or myocardial infarction within 6 months * History of cerebral infarction or cerebral hemorrhage within 6 months * There is a history of sustained systemic corticosteroid treatment within 1 month * Needs simultaneous surgical treatment of other diseases； * Gastric cancer complications (bleeding, perforation, obstruction) require emergency surgery * Pulmonary function test FEV\<1 predicted value 50%
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effects of quality of life | The quality of life questionnaire was conducted at six months after surgery. | The GSRS scoring system was used to understand the functional status of the digestive tract and its impact on quality of life in postoperative patients .The GSRS scoring system was 0-3, with 0 being the mildest and 3 being the most severe |
Countries
China
Outcome results
None listed