Influence of Umbilical Cord Clamping Time in the Newborn

Influence of Umbilical Cord Clamping Time in the Newborn, Secondary Neonatal Morbidity and Iron Deposits in the Neonate

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03624335

Enrollment

195

Registered

2018-08-10

Start date

2015-03-23

Completion date

2016-03-31

Last updated

2018-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anemia Neonatal, Polycythemia Secondary, Hyperbilirubinemia, Neonatal

Keywords

Umbilical cord clamping, Anemia Neonatal, Iron metabolism disorders

Brief summary

This study compares two umbilical cord clamping times; the early one, up to a minute (ECC) and the late or delayed one, when the cord stop beating (DCC). The additional blood volume delivered to the newborn from the placenta - placental transference - by delaying umbilical cord ligation, increases the contribution of neonatal iron with increased iron stores in the infant, without increasing neonatal morbidity.

Detailed description

It is an intervention study without drugs administration with a longitudinal, prospective comparison and correlational design. Patients are recruited by simple random sampling to one of the two intervention groups: Group 1-ECC: Early clamping of the umbilical cord (before the first minute of life). Group 2-DCC: Delayed clamping of the umbilical cord (when it stops beating).

Interventions

PROCEDUREECC

Early clamping of the umbilical cord

PROCEDUREDCC

Delayed clamping of the umbilical cord

PROCEDUREBlood Test 6hours

Blood Test 6hours

PROCEDUREBlood Test 24hours

Blood Test 24hours

PROCEDUREBlood Test 48hours

Blood Test 48hours

PROCEDUREBlood Test 28days

Blood Test 28days

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Intervention model description

Randomised controlled trials comparing early and late cord clamping

Eligibility

Sex/Gender

ALL

Age

35 Weeks to 42 Weeks

Healthy volunteers

Yes

Inclusion criteria

\- neonates with a gestational age of 35 to 42 weeks and born through normal vaginal delivery.

Exclusion criteria

* monochorionic multiples * incarcerated mothers * placenta previa * concern for abruptions * Rh sensitization * hydrops * congenital anomalies * the obstetrician declining to perform the intervention

Design outcomes

Primary

Measure	Time frame	Description
haemoglobin	6hours	haemoglobin level
haematocrit	6 hours	haematocrit level

Secondary

Measure	Time frame	Description
serum ferritin	6hours	serum ferritin level
bilirubin	6hours	bilirubin level

Countries

Spain

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 13, 2026