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Validation of a Universal Cataract Intelligence Platform

Validation of the Utility of a Universal Cataract Intelligence Platform

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03623971
Enrollment
500
Registered
2018-08-09
Start date
2013-01-01
Completion date
2017-06-01
Last updated
2018-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Artificial Intelligence, Cataract

Keywords

Cataract, Artificial Intelligence, Medical Referral Pattern

Brief summary

This study established and validated a universal artificial intelligence (AI) platform for collaborative management of cataracts involving multi-level clinical scenarios and explored an AI-based medical referral pattern to improve collaborative efficiency and resource coverage.The datasets were labeled using a three-step strategy: (1) categorize slit lamp photographs into four separate capture modes; (2) diagnose each photograph as a normal lens, cataract or a postoperative eye; and (3) based on etiology and severity, further classify each diagnosed photograph for a management strategy of referral or follow-up. A deep residual convolutional neural network (CS-ResCNN) was used for the image classification task. Moreover, we integrated the cataract AI agent with a real-world multi-level referral pattern involving self-monitoring at home, primary healthcare, and specialized hospital services.

Interventions

DEVICECataract AI agent

An artificial intelligence to make comprehensive evaluation and treatment decision of different types of cataracts.

Sponsors

Xidian University
CollaboratorOTHER
Sun Yat-sen University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Patients who underwent ophthalmic examination of the eye and recorded their ocular information in the primary healthcare center.

Exclusion criteria

The patients who cannot cooperate with the examinations.

Design outcomes

Primary

MeasureTime frameDescription
Diagnostic accuracy of the cataract AI agent6 monthsAUC: area under the receiver operating curve; accuracy (ACC) = (TP + TN) / (TP + TN + FP + FN); sensitivity (SEN) = TP / (TP + FN); specificity (SPE) = TN / (TN + FP); TP = true positive; TN = true negative; FP = false positive; FN = false negative.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026