Erosive Pustular Dermatosis of the Leg
Conditions
Keywords
Erosive pustular dermatosis of the leg, Erosive pustular dermatosis of the scalp, Venous insufficiency
Brief summary
Erosive pustular dermatosis of the leg is a fairlyrecent clinical entity that was described the first time in 1987. Diagnosis of erosive pustular dermatosis of the leg is made on clinical grounds. It presents as non-follicular pustules of variable size and numbers that rapidly give way to erosions and crusts on one or both legs, and which are found in particular on the anterior aspect of the middle third of the leg (. The lesions are of chronic progression, despite topical therapy. Erosive pustular dermatosis of the leg is seen in elderly patients, mainly female, and may be associated with chronic venous insufficiency or cutaneous atrophy. In the absence of specific criteria and because of the existence of misleading clinical forms, diagnosis is based upon exclusion.
Detailed description
The primary objective of this investigation was to describe the different clinical aspects of cases of Erosive pustular dermatosis of the leg.
Interventions
OTHERClinical examination
Sponsors
CHU de Reims
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
\- non-follicular pustules and multiple erosions on one or both legs showing no evidence of improvement after application of compression in the event of clinical signs of chronic venous insufficiency and showing no improvement following treatment with local and/or systemic antibacterial therapy, fungal samples from the pustules negative on direct examination, negative direct immunofluorescence results for biopsy samples (taken from around the lesion)
Exclusion criteria
\- age \< 18 years old
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| number of lesions | Day 0 | Less than 10 erosions, between 10 and 50 erosions and more than 50 erosions |
| Lesions location | Day 0 | Anterior or posterior leg face |
| Presence of chronic venous insufficiency | Day 0 | Diagnosis based on the CEAP 2004 Score (Eklöf B, Rutherford RB, Bergan JJ, Carpentier PH, GloviczkiP, Kistner RL, et al. Revision of the CEAP classification forchronic venous disorders: consensus statement. J Vasc Surg2004;40:1248-52) |
Countries
France
Outcome results
None listed