Brain Neoplasms
Conditions
Brief summary
In order to come as close as possible to the correct diagnosis of CNS tumors, MRI is the long-standing accepted method of choice that can in some cases be supported by the use of CT to demonstrate calcification or bone destruction. In individual cases MRI spectroscopy can be helpful for the differentiation between neoplasms and inflammatory lesions or surveillance of tumor therapy, just as perfusion
Detailed description
Proton magnetic resonance spectroscopy (H-MRS) may be helpful in suggesting tumor histology and tumor grade and may better define tumor extension and the ideal site for biopsy compared with conventional magnetic resonance (MR) imaging. A multifunctional approach with diffusion-weighted imaging, perfusion-weighted imaging, and permeability maps, along with H-MRS, may enhance the accuracy of the diagnosis and characterization of brain tumors and estimation of therapeutic response. Integration of advanced imaging techniques with conventional MR imaging and the clinical history help to improve the accuracy, sensitivity, and specificity in differentiating tumors and nonneoplastic lesions.
Interventions
DEVICEMRI Spectroscopy
Patient with brain SOL underwent MRI Spectroscopy to be compared with later pathology
Sponsors
Assiut University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Inclusion criteria
* All patients with space-occupying lesions
Exclusion criteria
* Post operative cases * Non-neoplastic nature
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison of MRS findings with the pathology of the specimens | Baseline | Analysis of the MRS metabolites peaks and integral and test if they can differentiate the grades of brain tumors |
Countries
Egypt
Contacts
Primary ContactMohamed AbdelWahab, Msc
Outcome results
None listed