Multiple Sclerosis, Neurological Diseases or Conditions, Sensory Disorders, Stroke
Conditions
Brief summary
The aim of this case-controlled observational cross-sectional study is to investigate the test-retest reliability, validity and clinical utility of a rapid robotic assessment of finger proprioception using a passive gauge position matching tasks in MS and stroke subjects. Session 1 Informed consent Descriptive measures Session 2 Clinical testing Robotic assessment (3x) Session 3 Clinical testing Robotic assessment (3x)
Interventions
OTHERRobotic assessment of finger proprioception
The assessment will be performed using a robotic device specifically designed for the assessment of finger proprioception at the metacarpophalangeal (MCP) joint .
Sponsors
Jessa Hospital
Revalidatie & MS Centrum Overpelt
Hasselt University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Inclusion criteria MS subjects * Age \> 18 years * Diagnosis of MS (McDonald criteria) * No relapse or relapse-related treatment within the last 3 months prior to the study Inclusion criteria Stroke subjects * Age \> 18 years * Diagnosis of stroke (ischemic or hemorrhagic), * Between 2 weeks and 12 months post-stroke
Exclusion criteria
* Complete paralysis of both upper limbs * Unable to detect any passive movement in hand and fingers * Unable to place the hand in the robotic devices without any discomfort or pain * Marked or severe intention tremor (Fahn's tremor rating scale on finger-to-nose test \> 3) * Marked or severe spasticity for finger and elbow flexors or shoulder adductors (Modified Asworth scale \>3) * Other medical conditions interfering with the hand function (peripheral nerve lesion, orthopedic or rheumatoid impairment, pain, edema) * Severe cognitive or visual deficits interfering with testing and training (e.g. Aphasia, neglect, …)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Error | day 2 | The extracted parameter is measured by the robotic device. The MCP angular position measured by the robot and the angle reported on the touchscreen by the subject. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Age | day 1 | age |
| medication use | day 1 | medication use at time of study |
| the modified Ashworth scale | day 1 | Spasticity of the upper limb will be evaluated with the modified Ashworth scale |
| Edinburgh Handedness Inventory | day 1 | Hand Dominance evaluated with Edinburgh Handedness Inventory |
| Nine Hole Peg test | day 1 | manual dexterity test |
| Box and block test | day 1 | gross and fine upper limb test |
| sex | day 1 | man/female |
| Symbol digit modalities test | day 1 | Cognitive function (Symbol digit modalities test) |
| 25 foot walk test | day 1 | Gait velocity test |
| Semmens-Weinstein monofilaments | day 1 | Tactile sensitivity in the fingers (Semmens-Weinstein monofilaments) |
| Rydel Seiffer Tuning fork | day 1 | Vibration in the upper limb (Rydel Seiffer Tuning fork) |
| The Erasmus MC modification of the Nottingham Sensory Assessment (EmNSA) | day 1 | Sensory function test |
| The System Usability Scale (SUS) | day 2 | Questionnaire |
| Manual Ability Measure-36 (questionnaire) | day 1 | Patient reported measure for upper limb use in daily life activities |
Countries
Belgium
Outcome results
None listed