A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer

Total Cancer Care Protocol: A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer (ORIEN)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03617939

Enrollment

20000

Registered

2018-08-07

Start date

2015-09-16

Completion date

2037-09-30

Last updated

2025-11-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer Risk

Keywords

Tissue Repository, Blood Samples, Biological Samples, Surveys, Early Detection, Risk Assessment

Brief summary

This is not a treatment study. The overall objective is to develop an improved standard of care through studying blood, tissue, biological, etc. samples, that patients have allowed researchers to procure.

Detailed description

The Oncology Research Information Exchange Network (ORIEN) hopes to establish a unique collection of blood, tissue, other biological samples and their associated data (survey data, medical records data, cancer registry data, and other related data) from thousands of patients with cancer or at risk of having cancer. Their hope is to, over time, facilitate new clinical trials, technology, informatics solutions, and personalized medicine to each cancer patient.

Interventions

PROCEDUREBiospeciman Collection

Collection of blood, tissue, and other biological samples.

OTHERSurvey Assessments

Data taken from patient surveys and assessments, including quality of life.

OTHERMedical Chart Reviews

Data taken directly from the patients' medical charts.

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. 18 years of age and older. 2. Diagnosed with cancer, or may be at risk for cancer. 3. Able to understand and sign the TCCP Informed Consent and Research Authorization form directly or through a legally authorized representative (LAR). Non-English speaking subjects will also be invited to participate in the TCCP study, in accordance with COMIRB's short-form consent use.

Exclusion criteria

1\. Members of vulnerable populations including neonates (birth to 30 days), children (under age 18), wards of the State, prisoners or those on probation or alternate sentencing, or decisionally challenged (adults or children that are cognitively impaired, incompetent to consent, proxy consent, or consenting in life threatening situations).

Design outcomes

Primary

Measure	Time frame	Description
Improve Standard of Cancer Care	Up to 20 years	Establish a longitudinal clinical and related data and tissue repository that will contain patient demographics via surveys and questionnaires.

Countries

United States

Contacts

Primary ContactKyra Anderson

kyra.anderson@cuanschutz.edu303-724-3868

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026