Hand Dermatoses
Conditions
Brief summary
Empirically, mosturizer is used to prevent and treat many occupational dermatoses that has skin barrier impairment. Evidence based medicine about the effectivity of mosturizer in occupational dermatoses is limited. Coconut oil is one of traditional substance that is used as a skin care. There is study shows that coconut oil is effective for atopic dermatitis treatment in children. Other studies are needed to assess the effectivity coconut oil mosturizer cream to overcome occupational hand dermatitis.
Detailed description
The aim of this study is to measure the effectivenes of coconut oil cream for batik workers who suffer from occupational hand dermatitis. The gloves that used as a protective equipment are made from rubber which have its own limitations. Therefore other interventions are needed to improve barrier skin.
Interventions
DRUGCocos Nucifera Whole
Applying the Cocos Nucifera Whole cream for 2 weeks, on both of arms. We evaluated the score of hand dermatitis using Hand Eczema Score Index ( HECSI), transepidermal water loss (TEWL), and Skin capacitance
Sponsors
Fakultas Kedokteran Universitas Indonesia
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)
Masking description
blinding had to be done by Clinical Research Supporting Unit Faculty of Medicine, Universitas Indonesia
Intervention model description
Batik traditional workers with occupational hand dermatitis using emolient for prevention
Eligibility
Sex/Gender
MALE
Age
25 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* signing the informed consent document before the study start * adult population include patients between the ages of 18 and 64 years who work in the dyeing and washing process more than 6 months. * suffering from occupational hand dermatitis that meet Mathias Criteria. * willing to obey the research protocol * willing to fill in diary periodically
Exclusion criteria
* having history of allergy or irritation caused by coconut oil or other mosturizer * suffering from symptoms including edema, exudation, crust, fissures, liver problems, and signs of infection * on corticosteroid treatment ( medium to high potency) or on systemic immunosuppressive therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical improvement of hand dermatitis measured by Hand Eczema Severity Index (HECSI) after using coconut oil | 14 days | Batik workers who had hand dermatitis was measured using HECSI score before and after intervention with coconut oil cream. They used the cream twice daily for 14 days |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Transepidermal water loss (TEWL) | 14 days | TEWL is the amount of water that passively evaporates through skin to the external environment |
| Skin capacitance | 14 days | Skin capacitance depends on the water content of the stratum corneum |
Countries
Indonesia
Outcome results
None listed