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The Effect of Different Gingival Biotypes on Dimensional Stability of Free Gingival Graft

The Effect Of Different Gingival Biotypes On Dimensional Stability Of Free Gingival Graft: A Comparative 6 Month Clinical Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03616197
Enrollment
30
Registered
2018-08-06
Start date
2016-08-31
Completion date
2018-07-31
Last updated
2018-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrophy, Gingival Recession

Keywords

gingival biotype of adjacent teeth, free gingival graft, shrinkage of graft

Brief summary

The aim of this study is to compare the effect of mesial and distal adjacent gingival biotypes of the tooth / teeth region of free gingival graft (FGG) on the shrinkage ratio of graft at 6 months postoperatively.

Detailed description

The concept of gingival and periodontal phenotype was established as a result of clinical observation of changes in facial keratinized tissue width and thickness .It has been reported that gingival or periodontal diseases may develop more frequently in patients with thin gingival biotypes and that thick-flat biotype in implant restorations is important in achieving a successful aesthetic treatment outcome. Free gingival graft (FGG) is a mucogingival surgical procedure that is successfully used in the presence of inadequate keratinized gingival width and gingival recession. It is thought that factors that may adversely affect the continuity of graft nutrition may be effective in graft shrinkage. These reasons can be listed as follows; graft thickness, traumatic surgical procedure, graft dehydration, and suturing procedure. There was no study investigating the effect of periodontal biotypes on graft contraction in the region adjacent to the FGG operation.

Interventions

PROCEDUREfree gingival graft

A horizontal incision was made along the mucogingival line with a scalpel number 15 to prepare a bed of periosteum and a thin immobilized connective tissue. The moving gingival tissues were removed coronally, and the bed was prepared so that the immobilized keratinized gingival tissue was preserved and the graft was placed apically. The template of the recipient region was placed in the donor region to be 2-3 mm more apically than the gingival margins of the teeth. The number of 15 scalpel was used to make incision at the template border and perpendicular to the keratinized tissue. The graft thickness was standardized in all patients between 1.5-2 mm. FGG was placed over the recipient bed and 5/0 non-resorbable monofilament sutures were used for fixing the four corners of the graft.

Sponsors

Istanbul Aydın University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Masking description

Determination of graft area measurements and shrinkage ratio of all photographs was performed by a periodontologist , an independent specialist who had not performed any surgical procedures.

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* In the mandibular incisor tooth / teeth, the attached keratinized gingival width is \<1 mm, * No periodontal surgery has been performed previously on the involved tooth. * In the absence of any systemic condition or illness (pregnancy, breastfeeding, mental retardation, diabetes, etc.) that may interfere with the patient's approval and dental treatment. * Do not use any of the drug groups that may cause gingival overgrowth.

Exclusion criteria

* Previous periodontal surgery in the operation area * Restoration of the buccal surface of the tooth and no pathology in the apical region of the tooth. * In the presence of any systemic condition or illness (pregnancy, breastfeeding, mental retardation, diabetes, etc.) that may interfere with the patient's approval and dental treatment.

Design outcomes

Primary

MeasureTime frameDescription
The graft shrinkage ratiobaseline - 6th months postoperativelyGraft shrinkage = Preoperative area - Postoperative area X 100 Preoperative area

Secondary

MeasureTime frameDescription
keratinized ginigival widthbaseline - 6th months postoperativelyKeratinized Gingival Width(KGW) was measured using a lugol solution (10% potassium iodide and 5% iodine) with a manual caliper spaced 0.5 mm from the mid-buccal point of the tooth, the distance between the gingival margin and mucogingival junction from MTT, DTT and the teeth/tooth in operation area.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026