Gastroesophageal Reflux Disease
Conditions
Keywords
gastoesophageal reflux disease, prevalence, Azerbaijan
Brief summary
To evaluate the prevalence of Gastroesophageal reflux disease in Azerbaijan. It is intended to evaluate the prevalence of the disease in the regions as well as the capital by cluster sampling ,ethitology and to compare the outcomes depending on the geographical location.
Detailed description
It is an observational, nationwide study. The GERD questionnaire (1994) requested from Mayo clinic, was received and validated. The questionnaire was translated by 3 individuals from english to azeri and back trasnlated by 3 native english speakers. Power analysis was performed. The research was presented for the approval to Ethical Committee of Azerbaijan Medical University. Prior to the actual study, a pilot study with smaller number of participants was performed and the results were evaluated. Cluster sampling methodology was provided by the statistical department of Azerbaijan Medical University. 110 employees were hired for using a survey in different regions of Azerbaijan. Written consent was obtained from every person evaluated. Statistical ananlysis was performed.
Interventions
None listed
Sponsors
Azerbaijan Medical University
Sevda Aghayeva
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Age: 18-80 * Both genders * Hearburn * Belching * Regurgitation
Exclusion criteria
* protom pomp inhibitor use * antibiotic use in the last 4 weeks * upper GI surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The prevalence of GERD in Azerbaijan | 1 year | The prevalence of GERD in Azerbaijan was 22.7% with significant female predominance (26.1% vs 15.3%; p\<0.0001). GERD was defined in 17 % for ages below 35; 22.7 % for 36-55 and 38.5 % for those who are above 56 that, accordingly, indicating that GERD becomes significant as age increases (p\<0.0001). Reflux was observed in 18.1% of normal weight respondents (BMI 18.6-24.9), 25.6% of overweight (BMI 25-29.9), and in 30.4% of obese (BMI\>30) individuals (p=0.001). Regarding marital status, the prevalence was the lowest in the single subjects' group (17%), close to average in the married group (23.8%), and the highest (41.7%) in divorced/widowed cases (p=0.003). Stress was significantly affecting GERD distribution, affecting 59.4% of all respondents (p\<0.004). |
| GERD questionnaire (GERD) of Mayo case 1998- 019 | 1 year | Observational study |
Countries
Azerbaijan
Outcome results
None listed