Out-of-Hospital Cardiac Arrest
Conditions
Brief summary
This study was performed to determine the prognosis of patients after cardiac arrest using serum markers called NGAL. The initial NGAL values of patients with post-cardiac arrest syndrome are checked by blood tests, and the long-term neurological prognosis and survival rate are collected after 6 months.
Detailed description
Serum NGAL is currently being used as a test to determine the likelihood of developing renal failure. However, in a previous study, serum NGAL correlated with neurological prognosis in post cardiac arrest syndrome patients. This prospective study attempts to see the role of serum NGAL as a prognostic factor by including a sufficient number of patients.
Interventions
DIAGNOSTIC_TESTserum NGAL
serum NGAL was measured at 0, 24, 48, and 72 hours after recovery of spontaneous circulation.
Sponsors
Uijeongbu St. Mary Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients who underwent targeted temperature management after out-of-hospital cardiac arrest.
Exclusion criteria
* Patients who did not survived 3 days after cardiac arrest. * Pre-existing end-stage renal disease or dependence on renal replacement therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Long term neurologic outcome | 6 months | Patients' CPC score after 6 months (good outcome : CPC score 1, 2 / poor outcome : CPC score 3, 4, 5) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of participants with Overall Survival at 6 months | 6 months | 6-month survival rate of patients' |
Countries
South Korea
Outcome results
None listed