Overactive Bladder, Non Obstructive Urinary Retention
Conditions
Brief summary
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth sacral foramen and stimulates sacral roots in its vicinity. Since the sacral roots are mixed nerves, it is currently still unknown which nerve fibers are stimulated (autonomic vs somatic, afferent vs efferent) and what the mechanism of action is. This study examines the involvement of pudendal somatic afferents by measuring somatosensory evoked potentials elicited by stimulation of the pudendal nerve.
Interventions
DIAGNOSTIC_TESTSomatosensory evoked potentials
Stimulation of the pudendal nerve while recording at the sensory cortex.
Sponsors
Universiteit Antwerpen
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Overactive bladder * Non-obstructive urinary retention
Exclusion criteria
* Neurogenic disorders (e.g. cerebrovascular accident, spinal cord injury,...)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Latency change | 3 weeks | Latency of somatosensory evoked potential are recorded before and after test procedure sacral neuromodulation expressed in milliseconds. |
Countries
Belgium
Contacts
Primary ContactDonald A Vaganee, MD PhD student
Backup ContactStefan De Wachter, MD PhD FEBU
Outcome results
None listed