Radio-frequency Ablation in Knee Osteoarthritis by Three Needles Technique

Three Needles Approach... A New Technique of Genicular Nerve Radio-frequency Ablation for Pain Relief in Advanced Knee Osteoarthritis

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03613610

Enrollment

Registered

2018-08-03

Start date

2018-02-26

Completion date

2018-11-30

Last updated

2018-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Genicular nerve radio-frequency ablation

Brief summary

The study is designed to evaluate and compare the efficacy of three needles approach as a new technique in radiofrequency neurotomy of genicular nerve versus the traditional single needle approach as a treatment of advanced knee osteoarthritic pain. Primary outcome: 1. Pain intensity via the visual analogue score (VAS). 2. Function and pain via the Oxford Knee Score. Evaluated after 6 months of the procedure Secondary outcome: 1. Failure rate. 2. Incidence of any complication. 3. Total analgesic requirement during the period of follow up.

Interventions

RADIATIONRadio-frequency ablation of genicular nerves

Ablation of the genicular nerves for pain relief in advanced knee osteoarthritis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

35 Years to 85 Years

Healthy volunteers

Inclusion criteria

* 1- Age 35-85 years old 2- Patients with stage 3 or higher OA-related radiological changes based on Kellgren-Lawrence (K/L) rating scale 3- Knee pain for at least 3 months 4-Patients are clinically unresponsive to conservative treatment modalities (physical therapy and rehabilitation practices, orally administered analgesics and anti-inflammatory drugs).

Exclusion criteria

* 1- Patients with other causes of pain as radiculopathy, neurological disorders or intermittent claudication. 2- Previous knee trauma. 3- Previous knee surgery. 4- Patients received intra-articular injection during the previous three months. 5- Acute knee pain. 6- Crystal arthropathy. 7- Joint effusion. 8- Serious neurological or psychiatric disorders. 9- On anticoagulant medication. 10- Any other connective tissue disorder that affects the knee joint. 11- skin infection at the site of injection. 12-patient refusal.

Design outcomes

Primary

Measure	Time frame	Description
Visual analogue score	6 months after the procedure	Pain intensity via the visual analogue score (VAS).
Oxford knee score	6 months after the procedure	Follow up of pain and function via the Oxford knee score

Secondary

Measure	Time frame	Description
Failure rate	6 months after the procedure	Persistence of pain after the procedure
Incidence of complication	6 months after the procedure	Any infection, heamatoma

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026