Prevalence Rates of USI, BO, DO and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Prevalence Rates of Urodynamic Stress Incontinence, Bladder Oversensitivity/Detrusor Overactivity or Both and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03613350

Enrollment

480

Registered

2018-08-03

Start date

2011-11-01

Completion date

2018-05-31

Last updated

2018-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower Urinary Tract Symptom in Severe Cystocele Women

Keywords

Cystocele, Urodynamic stress incontinence, Detrusor overactivity, Pad test, Urodynamic study

Brief summary

Prevalence rates of urodynamic stress incontinence (USI), bladder oversensitivity (BO) /detrusor overactivity (DO) or both and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation. Thus, the aim of this study was to elucidate the above findings and between-group associations.

Detailed description

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent 20-minute pad testing and urodynamic studies in a medical center were reviewed. ANOVA test and post-hoc testing with bonferroni's correction were used for statistical analysis. USI included evident USI and occult USI, which were classified according to pad weight before and after prolapse reduction. BO was defined as \<300 mL of the volume at strong desire to void during filling cystometry. Those women without USI, BO or DO were allocated into the no demonstrated USI+BO/DO group.

Interventions

DIAGNOSTIC_TESTPad test

20-minutes pad test and urodynamic study (including uroflowmetry, filling and voiding cystometry, and urethral pressure profile) were conducted to every patient.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Age \>20y/o 2. Severe cystocele, ie, more than stage 2 3. Complete pad test and urodynamic study

Exclusion criteria

1. Pregnancy 2. Urinary tract infection 3. Had received pelvic reconstruction

Design outcomes

Primary

Measure	Time frame	Description
USI	Between November 2011 and January 2017	Urodynamic stress incontinence was noted during examination
BO/DO	Between November 2011 and January 2017	Bladder oversensitivity/detrusor overactivity was noted during examination

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026