BOO and DU and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Prevalence Rates of Bladder Outlet Obstruction and Detrusor Underactivity and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03613324

Enrollment

455

Registered

2018-08-03

Start date

2011-01-01

Completion date

2018-05-31

Last updated

2018-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bladder Outlet Obstruction and Detrusor Underactivity in Women With Severe Cystocele

Keywords

Cystocele, Bladder outlet obstruction, Detrusor underactivity, Urodynamic study

Brief summary

Prevalence rates of bladder outlet obstruction (BOO) and detrusor underactivity (DU) and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification stage II cystocele are important for clinical consultation. Thus, the aim of this study was to elucidate the above findings and between-group associations.

Detailed description

Between November 2011 and January 2017, medical records of all women with ≥stage II cystocele who underwent 20 min pad testing and urodynamic studies in a medical center were reviewed. Only those with complete data of maximum flow rate (Qmax) and detrusor pressure at maximum flow rate (PdetQmax) were enrolled. ANOVA test and post-hoc testing with bonferroni's correction were used for statistical analysis. Woman were defined as having DU when Qmax was \<12 mL/s and PdetQmax was \<10 cmH2O, and were defined as having BOO when Qmax was \<12 mL/s and PdetQmax was ≥25 cmH2O with sustained detrusor contraction during voiding cystometry.

Interventions

DIAGNOSTIC_TESTPad test

20-minutes pad test and urodynamic study including uroflowmetry, filling cystometry and voiding cystometry.

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

20 Years to No maximum

Healthy volunteers

Inclusion criteria

1. Age \> 20y/o 2. Cystocele \> stage II 3. Complete pad test and urodynamic study

Exclusion criteria

1. Pregnancy 2. Urinary tract infection 3. Had received pelvic reconstruction surgery

Design outcomes

Primary

Measure	Time frame	Description
BOO	November 2011 to January 2017	Bladder outlet obstruction: Qmax was \<12 mL/s and PdetQmax was ≥25 cmH2O with sustained detrusor contraction during voiding cystometry.
DU	November 2011 to January 2017	Detrusor underactivity: \<12 mL/s and PdetQmax was \<10 cmH2O

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026