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Diastolic Blood Pressure and Lipid Profile in Infants

Diastolic Blood Pressure and Lipid Profile in Breastfed Vs. Formula Fed Infants ( As Early Indicators for Cardiovascular Disease ).

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03612427
Acronym
ERAhmed
Enrollment
120
Registered
2018-08-02
Start date
2018-08-01
Completion date
2019-12-01
Last updated
2018-08-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breastfeeding, Exclusive

Brief summary

The influence of early environmental factors, including nutrition, on future cardiovascular disease (CVD) risk and, in a broader view, the concept of early metabolic programming and future health have been extensively discussed during the past decades. Observational studies have suggested that formula-fed infants as compared with breastfed infants have an elevated risk of future CVD.

Detailed description

The influence of early environmental factors, including nutrition, on future cardiovascular disease (CVD) risk and, in a broader view, the concept of early metabolic programming and future health have been extensively discussed during the past decades. Observational studies have suggested that formula-fed infants as compared with breastfed infants have an elevated risk of future CVD, since they have faster early growth rate and higher risk of overweight, type 2 diabetes, high blood pressure, and unfavorable blood lipid profile in adult age. Formula-fed preterm infants have higher serum C-reactive protein (CRP) concentration, higher serum low-density lipoprotein to high-density lipoprotein (LDL:HDL) ratio, and higher serum apolipoprotein B to apolipoprotein A1 (apoB:apoA1) ratio in adolescence as compared with preterm infants receiving banked breast milk.

Interventions

DIETARY_SUPPLEMENTS. Cholesterol S. Triglyceride

S. Cholesterol S. Triglycerides

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
10 Months to 14 Months
Healthy volunteers
Yes

Inclusion criteria

1. Breastfed infants 2. Formula-fed infants 3. Raw milk fed infants 4. Mixed fed infants 1. Breast milk plus raw milk 2. Breast milk plus formula

Exclusion criteria

1\. Children with Cong. Heart Disease, family history of congenital hyperlipidemia and cases which prove hyperlipidemia of high levels (congenital).

Design outcomes

Primary

MeasureTime frameDescription
Diastolic blood pressureAround one yearValue of Infants feeding

Secondary

MeasureTime frameDescription
Serum cholesterol levelAround one yearValue of breastfeeding

Contacts

Primary ContactEl-Shazly Ahmed, MBBCh
Shazliahmed777@gmail.com01000690960

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026