Breastfeeding, Exclusive
Conditions
Brief summary
The influence of early environmental factors, including nutrition, on future cardiovascular disease (CVD) risk and, in a broader view, the concept of early metabolic programming and future health have been extensively discussed during the past decades. Observational studies have suggested that formula-fed infants as compared with breastfed infants have an elevated risk of future CVD.
Detailed description
The influence of early environmental factors, including nutrition, on future cardiovascular disease (CVD) risk and, in a broader view, the concept of early metabolic programming and future health have been extensively discussed during the past decades. Observational studies have suggested that formula-fed infants as compared with breastfed infants have an elevated risk of future CVD, since they have faster early growth rate and higher risk of overweight, type 2 diabetes, high blood pressure, and unfavorable blood lipid profile in adult age. Formula-fed preterm infants have higher serum C-reactive protein (CRP) concentration, higher serum low-density lipoprotein to high-density lipoprotein (LDL:HDL) ratio, and higher serum apolipoprotein B to apolipoprotein A1 (apoB:apoA1) ratio in adolescence as compared with preterm infants receiving banked breast milk.
Interventions
S. Cholesterol S. Triglycerides
Sponsors
Study design
Eligibility
Inclusion criteria
1. Breastfed infants 2. Formula-fed infants 3. Raw milk fed infants 4. Mixed fed infants 1. Breast milk plus raw milk 2. Breast milk plus formula
Exclusion criteria
1\. Children with Cong. Heart Disease, family history of congenital hyperlipidemia and cases which prove hyperlipidemia of high levels (congenital).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diastolic blood pressure | Around one year | Value of Infants feeding |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum cholesterol level | Around one year | Value of breastfeeding |