Structured Education, Type 1 Diabetes Mellitus
Conditions
Brief summary
This study aims to clarify the underlying hereditary and autoimmune factors that contribute to clinical type 1 diabetes and gain a better understanding of the natural history of the disease.
Interventions
OTHERtype 1 diabetes structured education
The structured education is based on a regular outpatients visit.It is an education that integrated several diabetes related subjects,which mainly aimed at T1D self-management.
Sponsors
Second Xiangya Hospital of Central South University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
1. diabetes diagnosed according to the report of WHO (World Health Organization) in 1999; 2. insulin dependence from disease onset,thus diagnosed with type 1 diabetes; 3. all patients gave informed consent to participate in the study and the protocol was approved by the Research Ethics Committee in second Xiangya hospital, Central South University.
Exclusion criteria
1. secondary diabetes mellitus; 2. pregnant women; 3. malignant disease.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Effects of structured education on β-cell endocrine function progression of T1D patients. | Baseline and every three months afterwards. | The natural progression of patients' β-cell endocrine functions was assessed by fasting C-peptide (FCP) and postprandial C-peptide (PCP) at each visit. FCP and PCP levels were measured at initial recruitment and every three months after that. The decay rate of β-cell endocrine function of patients in the two groups were compared. Serum C-peptide levels were measured by a chemiluminescence method using a commercial available kit (Adiva Centaur System, Siemens, Germany). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Effects of structured education on blood sugar control. | Baseline and every three months afterwards. | Patients' daily insulin dosage (U/Day) were collected at initial recruitment and each visit afterwards. And the above mentioned parameters in group 1(patients with structured education) and group2(patients without structured education) were compared. |
| Effects of structured education on metabolic control. | Baseline and every three months afterwards. | Patients' body mass index (BMI) levels were collected at initial recruitment and each visit afterwards. And the above mentioned parameters in group 1(patients with structured education) and group2(patients without structured education) were compared. |
Countries
China
Outcome results
None listed