Complication of Coronary Artery Bypass Graft, Complication of Extracorporeal Circulation
Conditions
Brief summary
A patient group receiving a novel cardioplegic formula with MPS ® (Myocardial protection system) and using the MiECC (Minimal extracorporeal circulation system) when undergoing coronary artery bypass grafting is compared to a retrospective patient group undergoing Off-pump coronary artery bypass grafting.
Interventions
PROCEDURECABG
CABG with application of a myocardial protection system (MPS ®) and using a minimal extracorporeal circulation system (MiECC) or CABG without use of a minimal extracorporeal circulation system (Off-pump coronary artery bypass grafting = OPCABG)
Sponsors
University Hospital, Basel, Switzerland
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* CABG using MPS® or OPCABG
Exclusion criteria
* use of other colloid solution than Cardioplexol ® for MPS® * other inventions than CABG * myocardial infarction \<7 days before CABG * patients denial of data use
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| assessment of cardial biomarkers as high sensitive troponin T (hs-TrT), Creatinkinase (CK) and Creatinkinase myocardial type (CK-MB) | perioperative during hospital stay for CABG | high sensitive troponin T (hs-TrT), Creatinkinase, (CK) Creatinkinase myocardial type (CK-MB) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| mortality | 30 days after CABG | death after coronary artery bypass grafting |
| need for intensive care unit | perioperative during hospital stay for CABG | duration of stay at intensive care unit |
| occurence of dysrhythmia | perioperative during hospital stay for CABG | rhythm disturbance after CABG |
Countries
Switzerland
Outcome results
None listed