End Stage Liver Disease
Conditions
Brief summary
Indications for splenectomy during whole liver transplantation remain controversial and splenectomy is often avoided because of common complications. The objective is to evaluate specific complications of these combined procedures.
Detailed description
Data on patients who underwent splenectomy during liver transplantation were retrospectively analyzed . Participants underwent splenectomy as part of routine medical care. Patients undergoing simultaneous liver transplantation and splenectomy were matched to a non-splenectomy group.
Interventions
PROCEDURESplenectomy
Splenectomy was performed after hepatectomy, in an extra-hilar manner with manual ligation of splenic vessels.
Sponsors
Hospices Civils de Lyon
Study design
Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Inclusion criteria
* Patients undergoing liver transplantation between 1994 and 2013
Exclusion criteria
* Data from living donor patients, split liver transplantation, patients with pre- or post-operative splenectomy in medical history, and patients under 16 years were excluded from analysis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3-month post-operative mortality | At 3 months post surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative morbidity | 3 months post surgery | Incidence of portal-vein thrombosis within 3 months post liver transplantation |
| One-year mortality | One year after surgery | — |
| Mortality at 5 years | Five years after surgery | — |
Countries
France
Outcome results
None listed