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Integrated Hypertension and HIV Care Cascades in Uganda

Integrated Hypertension and HIV Care Cascades in a HIV Treatment Program in Eastern Uganda: a Retrospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03605043
Enrollment
1649
Registered
2018-07-30
Start date
2014-01-01
Completion date
2018-05-30
Last updated
2018-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV, Hypertension

Keywords

Integrated, Care cascade, Uganda

Brief summary

In this retrospective cohort study, we mapped the care cascades for both Hypertension and HIV within a HIV program in Uganda with the goal of identifying opportunities for developing contextually appropriate integrated care models, .

Detailed description

Persons living with HIV (PLHIV) and receiving anti-retroviral therapy (ART) are at increased risk of cardiovascular disease (CVD) due to direct effects of ART and HIV infection itself, compounded by traditional CVD risk factors such as increased life expectancy and Westernized diet. Additionally, in sub-Saharan Africa, as is the case globally, hypertension (HTN) is a major risk factor for CVD. The prevalence of HTN in the setting of HIV reported in the literature is variable but may be higher than in the HIV-negative population. World Health Organization (WHO) and Ugandan national HIV guidelines have recommended the integration of hypertension care into HIV programs since 2014 and 2016, but there has been limited uptake of this recommendation in practice. There have been successful efforts to integrate tuberculosis, malaria, nutrition, maternal-child health, and family planning into HIV programmes in Uganda. In this study, with the goal of identifying opportunities for developing contextually appropriate integrated care models, we mapped the care cascades for both HTN and HIV within a HIV program in Uganda.

Interventions

OTHERBlood pressure management in the HIV program

Integrated care for hypertension and HIV in the HIV program

Sponsors

Makerere University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years of age and above, Having started Antiretroviral therapy between January 2014 and January 2017.

Exclusion criteria

* PLHIV receiving treatment from clinics other than the 3 selected sites.

Design outcomes

Primary

MeasureTime frameDescription
Blood pressure control1 yearBlood pressure control among Persons living with both HIV and hypertension. Achieving Blood pressure of \<140/90mmHg

Secondary

MeasureTime frameDescription
HIV control1 yearHIV control among persons living with both HIV and hypertension. Defined as HIV Viral suppression. Viral load of \<1000 copies/mL

Countries

Uganda

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026