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Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma

Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma: A Single-institutional Experience

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03604601
Enrollment
54
Registered
2018-07-27
Start date
2016-06-01
Completion date
2018-06-01
Last updated
2018-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Laryngeal Carcinoma

Keywords

salvage surgery, recurrent laryngeal carcinoma, experience

Brief summary

Early laryngeal cancer can be treatment by laser surgery or radiotherapy, intermediate and advanced laryngeal carcinoma mainly surgical treatment. Laryngeal cancer is at risk of recurrence after treatment, whether in surgery, laser or radiotherapy. The recurrence rate of laryngeal cancer is about 10% reported at home and abroad. Local pain, ulcers, breathing and eating difficulties caused by recurrent laryngeal cancer seriously reduce the quality of life of patients and seriously endanger their lives. Therefore, head and neck surgeons are required to make every effort to give them saving treatment in order to improve their quality of life. Prolong the patient's life.

Detailed description

medical records and extracted information including age, gender, initial treatment modality of glottis cancer, recurrence time, recurrence site, histopathology, tumor grade according to World Health Organization (WHO) grade and tumor stage. Stages were defined according to the American Joint Committee on Cancer (AJCC) staging system.

Interventions

Salvage surgery hopes to control the recurrence of larynx, pharynx, fistula and neck tumor and improve the quality of life and survival rate

Sponsors

First Affiliated Hospital, Sun Yat-Sen University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* more than 18 years, * patients with recurrent glottic laryngeal squamous cell carcinoma undergoing salvage surgery

Exclusion criteria

* postoperative radiotherapy and chemotherapy * loss to follow-up

Design outcomes

Primary

MeasureTime frameDescription
overall survival (OS)Follow up 5 yearsThe overall survival rate was calculated with Kaplan-Meier method.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026