Aortic Insufficiency, Aortic Stenosis, Insufficiency, Pulmonary, Insufficiency, Tricuspid, Mitral Insufficiency, Mitral Insufficiency and Aortic Stenosis, Tricuspid Regurgitation
Conditions
Brief summary
Background: Computer aided auscultation in the differentiation of pathologic (AHA class I) from no- or innocent murmurs (AHA class III) via artificial intelligence algorithms could be a useful tool to assist healthcare providers in identifying pathological heart murmurs and may avoid unnecessary referrals to medical specialists. Objective: Assess the quality of the artificial intelligence (AI) algorithm that autonomously detects and classifies heart murmurs as either pathologic (AHA class I) or as no- or innocent (AHA class III). Hypothesis: The algorithm used in this study is able to analyze and identify pathologic heart murmurs (AHA class I) in an adult population with valve defects with a similar sensitivity compared to medical specialist. Methods: Each patient is auscultated and diagnosed independently by a medical specialist by means of standard auscultation. Auscultation findings are verified via gold-standard echocardiogram diagnosis. For each patient, a phonocardiogram (PCG) - a digital recording of the heart sounds - is acquired. The recordings are later analyzed using the AI algorithm. The algorithm results are compared to the findings of the medical professionals as well as to the echocardiogram findings.
Interventions
Automated AI algorithm-based analysis of digital heart sound recordings to detect pathological heart murmurs. Heart sound recordings were fully blinded before undergoing one-time automated analysis. Algorithm results for each recording included: AHA classification (I pathologic versus III innocent/no murmur), murmur timing, murmur grade, heart rate and S1/S2 identification.
Sponsors
Study design
Eligibility
Inclusion criteria
* Adults with a heart defect verified by echocardiography
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Sensitivity for pathological heart murmur detection | 2 months | Ability to detect a pathological heart murmur in digital heart sound recordings obtained from an elderly population with heart valve disease. |
Countries
Austria