Fluid and Electrolyte Imbalance, Fluid Therapy
Conditions
Keywords
Rehydration Solutions
Brief summary
The investigators will study the correlation between the lenght of the fasting before surgery and the need to replenish with intra-venous fluids in children, evaluated with 3 measures of the aortic Integral Time Velocity with transthoracic echocardiography.
Interventions
OTHERPlasmalyte A Viaflo
Fluid therapy to be given according to the principle of 4-2-1 (4 ml of crystalloid fluid for each of the first 10 kg of weight (0-10 kg), 2 ml of crystalloid fluid for each of the second 10 kg of weight (11-20 kg) and 1 ml of crystalloid fluid for each kg of weight over 20.
Sponsors
Erasme University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
2 Years to 6 Years
Healthy volunteers
Yes
Inclusion criteria
* Children aged between 3 and 6 years with a normal ponderal evolution. * Children with good general status (ASA 1) * Children whose parents have given the informed authorization to do the study. * Children seen in the consultation of anesthesiology. * Children programed to have ambulatory surgery (Amygdalectomy, dental care, dental extraction).
Exclusion criteria
* Children with more than 6 years of age. * Children whose parents didn't agree with the study. * Children enrolled in another study on the 3 months before. * Children with hearth or lung conditions.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Aortic VTI change | From baseline analysis (t=5 min after anesthesia induction), to the end of fluid therapy (t=20 min). | Transthoracic echocardiography measures of the Time-Speed Interval in the aortic valve before fluid therapy (baseline) and after fluid therapy (20 ml/kg in 15 minutes). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Blood pressure change | From baseline analysis (t=5 min after anesthesia induction), to the end of fluid therapy (t=20 min). | Analysis of the variation of Mean Arterial Blood pressure with fluid therapy |
| Legs-up maneuver | From baseline analysis (t=5 min after anesthesia induction), to the end of legs-up maneuver (t = +/- 10 min). | Analysis of the variation of Mean Arterial Blood pressure with the legs up maneuver |
| Post-operative nausea and vomiting | From arrival at PACU (end of surgery) until discharge from PACU (tipically after 1 to 2 hours after the arrival to the PACU) | Comparisson of the incidence of post-operative nausea and vomiting in the fluid respondeurs group vs non respondeurs. |
Countries
Belgium
Contacts
Primary ContactIonut Tabolcea, MD
Backup ContactWendy Fernandez, MD
Outcome results
None listed