The Volume Effect of Hydrodissection for Carpal Tunnel Syndrome

The Volume Effect of Hydrodissection for Injection Therapies in Patients With Carpal Tunnel Syndrome - Evaluation Model by Shear Wave Ultrasound Elastography and Artificial Intelligence Imaging Analysis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03598322

Enrollment

Registered

2018-07-26

Start date

2018-06-30

Completion date

2019-07-30

Last updated

2019-09-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal Tunnel Syndrome

Brief summary

The investigators investigated the volume effect of hydrodissection for Injection therapies in patients with Carpal Tunnel Syndrome. The investigators evaluated participants by Shear Wave Ultrasound Elastography and Artificial Intelligence Imaging Analysis

Detailed description

Interventions

PROCEDUREDextrose 1mL injection

Dextrose 1mL injection and hydrodissection for CTS

PROCEDUREDextrose 2mL injection

Dextrose 2mL injection

PROCEDUREDextrose 4mL injection

Dextrose 4mL injection

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

20 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Age 20-80 * Electrophysiological diagnosis of carpal tunnel syndrome * At least one of the following two: 1. Tenderness or numbness over median nerve innervated dermatome over 2 months 2. Phalen test or Tinel sign or flick sign positive

Exclusion criteria

* History of wrist surgery * Wrist trauma in recent two years * Received wrist injection in recent three months * History of brachial plexopathy, cervical radiculopathy or thoracic outlet syndrome * History of DM, thyroid disorder or autoimmune disease * Unable to cooperate with interview, examination or injection

Design outcomes

Primary

Measure	Time frame	Description
Change of Visual analog scale (VAS)	1 week, 4 weeks, 12 weeks, 24 weeks	Change of Visual analog scale (VAS), from Baseline

Secondary

Measure	Time frame	Description
Boston Carpal Tunnel Syndrome Questionnaire Score (BCTQ)	1 week, 4 weeks, 12 weeks, 24 weeks	Boston Carpal Tunnel Syndrome Questionnaire Score (BCTQ), 19 items with each item scale 1-5
QuickDASH	1 week, 4 weeks, 12 weeks, 24 weeks	QuickDASH (The Disabilities of the Arm, Shoulder and Hand Score(QuickDash)), 11 items with each item scale 1-5
MSK US finding	1 week, 4 weeks, 12 weeks, 24 weeks	Cross-sectional area of median nerve

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 16, 2026