Acute Kidney Injury, Renal Resistive Index, Sepsis
Conditions
Keywords
ICU, Renal Resistive Index, Acute Kidney Injury, Sepsis
Brief summary
Purpose: The aim of this study was to assess the ability of early discrimination between transient and persistent Acute Kidney Injury (AKI) using the color Doppler Ultrasound derived Renal Resistive Index (RI) and semi-quantitative evaluation of intra-renal vascularization in septic patients in an Intensive Care Unit (ICU). Methods: Prospective observational cohort study with unselected, with 32 adult consecutive septic patients. Patients were divided into 3 groups: Group 1: patients without progression to AKI, Group 2: transient AKI, Group 3: persistent AKI.
Detailed description
Purpose: The aim of this study was to assess the ability of early discrimination between transient and persistent AKI using the color Doppler Ultrasound derived Renal Resistive Index (RI) and semi-quantitative evaluation of intra-renal vascularization in septic patients in an Intensive Care Unit (ICU). Additionally, the investigators aimed to identify whether these indexes are early predictors of the prognosis of renal function in this group of patients. And compare the diagnostic accuracy of those and other renal indexes for the identification of AKI reversibility. Methods: This was a prospective observational cohort study with unselected, consecutive septic patients included. Thirty-two adult septic patients hospitalized in a general ICU were studied. After the determination of sepsis, patients were divided into 3 groups: Group 1 included patients without progression to AKI, Group 2 included patients with transient AKI and Group 3 patients with persistent AKI.
Interventions
Use of color Doppler Ultrasound derived Renal Resistive Index (RI) and semi-quantitative evaluation of intra-renal vascularization for early prognosis of AKI progression
Sponsors
Study design
Eligibility
Inclusion criteria
* Septic patients in ICU * Age 18 years or older
Exclusion criteria
* ICU stay less than 3 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| RI as a prognostic factor for AKI persistence | 3 days | without units (range 0 to 1) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| semi-quantitative US evaluation of renal vasculature | 3 days | without units (score from 1 to 4) |
| FENa (Fractional Excretion of Sodium) | 3 days | % percentage |
Countries
Greece