Multiple Sclerosis
Conditions
Keywords
neurodynamics, pain
Brief summary
A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual dexterity in patients with multiple sclerosis
Interventions
OTHERPhysical Therapy
Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week.
OTHERPhysical Therapy plus Neurodynamic
Patients will receive 5 session of multimodal physiotherapy treatment of 30min duration including low-load strength exercises, soft tissue mobilization and muscle-tendon stretching exercises twice per week. In addition, they will also receive bilateral nerve slider neurodynamic interventions targeting the median, ulnar and radial nerves.
Sponsors
Universidad Rey Juan Carlos
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* a diagnosis of multiple sclerosis according to the modified McDonald criteria; * symptoms of paresthesia and lack of sensitivity in the upper extremity; * Expanded Disability Status Scale (EDSS) between 0 and 6.5 points; * absence of cognitive deficit.
Exclusion criteria
* any exacerbation of multiple sclerosis during the previous 3 months; * previous hand surgery or steroid injections treatment in the upper extremity; * multiple diagnoses on the upper extremity (e.g., cervical radiculopathy); * cervical, shoulder, or upper extremity trauma; * other comorbid musculoskeletal medical conditions; * mini-mental state examination \<25
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes in pressure pain sensitivity | Baseline and one week after the last treatment session | Pressure pain threshold over the median, ulnar and radial nerves, second metacarpal and tibialis anterior |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes in upper extremity pain intensity before and after the intervention | Baseline and one week after the last treatment session | A Numerical Pain Rate Scale (NPRS, 0-10) will be used to record the mean and the worst intensity of pain in te upper extremity |
| Changes in light touch detection threshold | Baseline and after treatmentBaseline and one week after the last treatment session | Light touch detection threshold will be assessed with a standardized set of modified twenty von Frey hairs |
| Changes in manual dexterity | Baseline and one week after the last treatment session | Bilateral manual dexterity was bilaterally assessed using the nine-hole peg test |
Countries
Spain
Outcome results
None listed