The Management of Neuroendocrine Tumours: A Nutritional Viewpoint.

Association Between Mediterranean Diet and Neuroendocrine Tumours.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03592940

Acronym

NetNutr

Enrollment

100

Registered

2018-07-19

Start date

2017-11-01

Completion date

2018-06-30

Last updated

2018-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mediterranean Diet, Neuroendocrine Tumours (NETs)

Brief summary

Nutritional status in patients with neuroendocrine tumours (NETs), especially of gastroenteropancreatic origin, can be deeply affected by excessive production of gastrointestinal hormones, peptides, and amines, which can lead to malabsorption, diarrhoea, steatorrhea, and altered gastrointestinal motility. Besides, the surgical and/or medical management of NETs can lead to alteration of gastrointestinal secretory, motor, and absorptive functions, with both dietary and nutritional consequences. Indeed, disease-related malnutrition is a frequently encountered yet both underrecognized and understudied clinical phenomenon in patients with NETs, with substantial prognostic and socioeconomic consequences. Most of these conditions can be alleviated by a tailored nutritional approach, also with the aim of improving the efficacy of cancer treatments. In this setting, skilled nutritionists can play a fundamental role in the multidisciplinary health care team in NETs management and their presence should be recommended.

Interventions

DIETARY_SUPPLEMENTMediterranean diet

We aim to determine the effects of the traditional Mediterranean Diet on neuroendocrine tumours

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Inclusion criteria

* patients with neuroendocrine tumours (NETs)

Exclusion criteria

* age\>65 years * \< BMI 19 kg/m2 * vegetarians

Design outcomes

Primary

Measure	Time frame	Description
Adherence to Mediterranean Diet by Predimed Questionnaire	December 2017 to June 2018	Validated 14-item tool of adherence to the Mediterranean diet, with three categories of adherence (≤5, low adherence, 6-9, average adherence and ≥10 points, high adherence)

Secondary

Measure	Time frame	Description
Body composition	December 2017 to June 2018	BIA was performed using a BIA phase-sensitive system by experienced observers (an 800-µA current at a frequency single-frequency of 50 kHz BIA 101 RJL, Akern Bioresearch, Florence, Italy)

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026