Heart Diseases
Conditions
Brief summary
The study is about comparing blood samples obtained from the superior vena cava and the pulmonary artery. The investigators will compare the values of PCO2 and PO2 from these two sites, in order to see if exists a PCO2 gap and a PO2 gap, different from zero. Moreover the investigators want to find out if these gaps are related with changes in the cardiac output, the hematocrit or if they can predict post operative dysfunctions. Blood samples will be taken at six different times as scheduled by the protocol. Along with the two venous blood samples, an arterial blood sample will be taken too, from a radial of femoral artery catheter.
Interventions
OTHERblood samples
blood samples will be obtained from the superior vena cava (via centra venous catheter), from the pulmonary artery (via Swan Ganz catheter), and from a radial or femoral artery catheter
Sponsors
Catholic University of the Sacred Heart
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \> 18 years * patient undergoing cardiac surgery with extracorporeal circulation * hemodynamic monitoring with a central venous catheter and a Swan Ganz catheter placed in the internal left giugulare vein
Exclusion criteria
* severe tricuspid insufficiency * EF \< 50% * SOFA score \>1 in at least one of all the criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PO2 gap changes | two days | See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery |
| PCO2 gap changes | two days | See if exists a PCO2 pa-svc gap different from zero in patients undergoing cardiac surgery |
Countries
Italy
Outcome results
None listed