Fine Motor Skill Dysfunction, Parkinson Disease
Conditions
Keywords
hand function, dual task, Parkinson disease, activities of daily living
Brief summary
This study was planned to investigate the contribution of dual task interference on dexterity related ADL disability in patients with Parkinson's disease. We hypothesised that the dual task interference is an indicator of dexterity related ADL difficulties.
Detailed description
We planned this study as a cross sectional trial. 53 patients with Parkinson's disease will be evaluated under 2 different task by nine hole peg test. Besides this assessment the cardinal symptoms (bradykinesia, tremor, rigidity) will be evaluated to determine their contribution on the ADL performance.
Interventions
DIAGNOSTIC_TESTFine motor dexterity test, nine hole peg test
The nine hole peg test will be performed under two different task (1)single task, (2)adding a cognitive task
Sponsors
Ordu University
Study design
Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* Diagnosis of idiopathic Parkinson's disease according to the criteria of the United Kingdom brain Bank by neurologist * Age 50-90 range * having sufficient cognitive status according to the Mini Mental Status Evaluation (24 or above from the Mini Mental Test)
Exclusion criteria
* Having orthopedic and neurological disorders affecting hand function, * Having sensory problems, * Having Diabetus mellitus
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nine hole peg test | 5 minutes | The Nine-Hole Peg Test is used to measure finger dexterity in patients with various neurological diagnoses. The patient must pick up the pegs from the holes and replace them back as fast as possible. The Nine Hole Peg Test should be conducted with the dominant arm first, then nondominant hand. The time will be recorded in second to complete the test. The test will be performed under three task; 1. single task: Only nine-hole peg test 2. adding a cognitive task: Nine-hole peg test will be performed with a concurrent cognitive task. The cognitive task is a serial 7 subtraction from numbers changed between 290 and 310 during the performing nine-hole peg test. The time will be recorded. |
| ADL-related dexterity Questionnaire 24 (DextQ-24) | 10 minutes | Dexterity-related ADL difficulties were measured by the ADL-related dexterity Questionnaire 24 (DextQ-24), including 24 question dealing with bimanual and unimanual activities, which is a reliable and valid disease specific questionnaire to evaluate dexterity in patients with PD. Each question is scored between 1 (no problems) and 4 (need aid to perform task) by the patient's experience. Total score ranged from 24 points to 96 points. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Modified Hoehn and Yahr Scale | 2 minutes | Disease progression will be assessed with modified Hoehn and Yahr Scale. The original scale included stages 1 through 5. Since then, stage 0 has been added, and stages 1.5 and 2.5 have been proposed. This modified scale allocates stages from 0 to 5 to indicate the relative level of disability. Stage 0: No signs of disease. Stage 1: Unilateral symptoms only. Stage 1.5: Unilateral and axial involvement. Stage 2: Bilateral symptoms. No impairment of balance. Stage 2.5: Mild bilateral disease with recovery on pull test. Stage 3: Balance impairment. Mild to moderate disease. Physically independent. Stage 4: Severe disability, but still able to walk or stand unassisted. Stage 5: Needing a wheelchair or bedridden unless assisted. |
| Unified Parkinson's Disease Rating Scale (UPDRS) - Section of Activities of Daily Living (ADL) | 10 minutes | The UPDRS- ADL section evaluates the impact of Parkinson disease on ADL according to patient's perspective. The ADL section consists of 13 items for gathering information on the patient's own perception of functional impairment due to PD. Each item scores between 0-4. 0 means normal and 4 means severe impairment. The total score change between 0-52. High scores indicate severe impairment. |
| Unified Parkinson's Disease Rating Scale (UPDRS) - Motor Section | 10 minutes | Motor section of UPDRS determines the impairment due to the Parkinson's disease. Rigidity, bradykinesia and tremor items which are relating with upper extremity function will be assessed. Each item scores between 0-4. 0 means normal and 4 means severe impairment. The total scores of rigidity, bradykinesia, and tremor, respectively range between 0-8, 0-24 and 0-16. |
Countries
Turkey (Türkiye)
Outcome results
None listed