Elderly Infection, Nutritional Supplement Toxicity, Nutrition Disorders in Old Age
Conditions
Keywords
nutritional status, Nutridrink, elderly nutrition
Brief summary
The study compares nutritional status of two groups elderly patient aged 65 and more. One group of the patients received nutritional support (Nutridrink Multi Fibre) for 14 days. Nutritional status of the patients were compared 2 months after the start of the intervention.
Detailed description
The aim of the study was to compare nutritional status of two groups of elderly patients (\> 65 years old). Total of 120 patients were randomly assigned into two groups. One group received normal diet whereas the second group received 300 kcal nutritional support (Nutridrink Multi Fibre 2x100 ml) between meals for 14 days. Two months after start of the intervention following examinations were performed: * functional status of the patient (Barthel's scale, MMSE scale) * nutritional status based on: weight, height, BMI; Mini Nutritional Assessment, plasma concentration of prealbumin, albumin, transferrin, total lymphocyte count. The clinical status of the patient was evaluated based on clinical data on different organ infections. In addition costs of supplementary nutrition were taken into consideration.
Interventions
DIETARY_SUPPLEMENTNutridrink Multi Fibre
Dietary supplementation of 300 kcal for 14 days
Sponsors
Radoslaw Pach, MD, Ph D
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Normal diet versus normal diet + nutritional support in elderly patients
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* age \> 65 and general status which enables compliance with study requirements * Barthel's scale (Barthel scale = Barthel ADL index - an ordinal scale used to measure performance in activities of daily living) points 21-100 * MMSE (Mini Mental State Examination) points 24-30 * no use of laxatives
Exclusion criteria
* lack of consent * neoplasms * previous enteral nutrition * Barthel's scale 0-20 * MMSE points 0-23 * BMI \> 25 * laxatives
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| TLC | 2 months | Total lymphocyte count two months after start of the intervention |
| BMI of the elderly patients | 2 months | BMI two months after start of the intervention |
| Prealbumin plasma concentration | 2 months | Prealbumin concentration two months after start of the intervention |
| Albumin plasma concentration | 2months | Albumin concentration two months after start of the intervention |
| Transferrin plasma concentration | 2 months | Transferrin concentration two months after start of the intervention |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complications | 2 months | Any complications associated with nutritional support |
| Functional status of the patient - Barthel's scale | 2 months | Scores in Barthel's scale two months after start of the intervention |
| Functional status of the patient - MMSE scale | 2 months | Scores in MMSE scale two months after start of the intervention |
| Organ infections | 2 months | Infection in any organ based on clinical data |
Outcome results
None listed