Pronostic Impact of Flow Fraction Reserve on Intermediate Stenoses

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03588455

Enrollment

Registered

2018-07-17

Start date

2018-01-01

Completion date

2018-06-30

Last updated

2018-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Stenosis

Brief summary

The intermediate coronary stenoses defined by a degree of stenosis from 40 to 70 % are frequent. The Flow Fraction Reserve (FFR), realized during coronarography, is an hemodynamic evaluation by the functional impact measuring the loss of load in upstream / approval of the stenosis inthe basal state and in situation of hyperemia led by adenosine. Further to the study FAME, the threshold of definition of the significant character of one Stenosis was fixed for a value of FFR = 0,80. However, the impact forecasts intermediate values badly known rest. We hypothetized that coronary stenosis associated with borderline values of FFR 0.81-0.85 were associated with a higher rate of clinical events than those with a FFR \>0.85

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patient with FFR\> 0,80 between september 2012 till december 2016

Exclusion criteria

* refusal of participation

Design outcomes

Primary

Measure	Time frame	Description
Composite outcome	3 years	cardiovascular mortality or acute coronary syndrom or revascularization or cardiovascular rehospitalisation

Countries

France

Outcome results