Vaccination
Conditions
Keywords
vaccination coverage
Brief summary
In France, vaccination coverage is insufficient (in 2002, 71.2% coverage for tetanus, 41.9% for poliomyelitis and 33.7% for diphteria). These numbers decrease significantly with age: coverage for people aged over 65 was 60.5%, 13.3% and 10.5% for tetanus, poliomyelitis and diphteria coverage respectively. The primary objective of this study is to evaluate the impact of a hospital based vaccination remedial strategy for Tdap-IPV (tetanus, diphteria, pertussis and polio vaccine) in patients 65 years of age or older. Secondary objectives are to measure the vaccination coverage of patients aged 65 years or older hospitalised in a medical ward in our hospital, to evaluate their knowledge of their vaccination coverage, and to evaluate the socio-demographic factors associated with vaccination coverage.
Interventions
BIOLOGICALRemedial vaccination
* if the patients vaccinations are up to date: no remedial vaccination is done and the patient is informed of the next remedial vaccination date * if the patients vaccinations are not up to date: remedial vaccination is realised in the unit in the absence of contraindication, in case of a temporary contraindication the vaccination will be performed on an outpatient basis by the patients primary care provider and he will be given a prescription at hospital discharge for the remedial vaccination.
Sponsors
Centre Hospitalier le Mans
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
Single center, prospective, cluster randomized trial.
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 65 years or older * Patients capable of understanding and giving informed consent to participate in the study * Valid social security coverage
Exclusion criteria
* Patients under judicial safeguard measures * Refusal to participate in the study * Vaccination contra-indication * Patient already included in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in immunization rate after a hospital centered remedial strategy for Tdap-IPV vaccination in patients 65 years or older | two months | Difference in the increase in vaccination coverage between the two arms, measured as a percentage |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Immunisation rate according to socio professional category | two months | Socio professional category defined according to the French national institute for statistics and economic studies (INSEE) |
| Immunisation rate among patients 65 years of age or older in the Sarthe department of France | two months | Pre-intervention vaccination coverage rate in both arms, measured as a percentage |
| Immunisation rate according to sex among patients 65 years or older | two months | Sex of patients included in the study |
| Immunisation rate according to primary care coverage among patients 65 years of age or older | two months | Primary care coverage is defined as having a regular primary care physician registered as such with French social security. |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORSophie Blanchi, M.D.
Centre Hospitalier du Mans
Outcome results
None listed