Polycystic Ovary Syndrome
Conditions
Keywords
amylin; obesity; polycystic ovarian syndrome; preptin
Brief summary
Preptin and amylin are pancreatic hormones which participate in glucose homeostasis. This study aims to evaluate how serum preptin and amylin levels are altered in polycystic ovary syndrome (PCOS) patients and healthy women based on BMI groups .
Detailed description
Materials and Methods: This is a cross-sectional review of 40 PCOS patients and 40 healthy women who were matched with respect to BMI (\<25 kg/m2 and ≥25 kg/m2).
Interventions
we will take both of group blood samples to compare them serum preptin and amylin
Sponsors
Study design
Eligibility
Inclusion criteria
the patients with PCOS
Exclusion criteria
Cushing's syndrome 21-hydroxylase deficiency Congenital adrenal hyperplasia Thyroid dysfunction Hyperprolactinemia Diabetes Chronic cardiovascular Hepatic, renal, and hematologic diseases Malignancies Using oral contraceptives, anti-androgens, glucocorticoids, anti-hypertensives, anti-diabetics, calcium supplements and anti-obesity drugs and those who smoke or consume alcohol \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum Preptin and Amylin Levels with Respect to Body Mass Index in Polycystic Ovary Syndrome Patients | six months | Serum Preptin and Amylin Levels will compare between groups |
Countries
Turkey (Türkiye)