Keratitis
Conditions
Keywords
Keratitis, Eye Infection, Photophobia, Red light, Infrared light
Brief summary
In order to develop an innovative device to study infectious keratitis, we need to illuminate the cornea of patients suffering from an infectious keratitis with red or near-infrared light. Because of technical reasons the shortest possible wavelength (red) presents advantages.
Detailed description
The aim of this preliminary study is to measure the maximal intensity tolerated during illumination with 6 wavelength corresponding : 2 red, 2 far red and 1 near infrared lights in order to determine the shortest wavelength well tolerated by patients, in comparison with the standard blue light illumination.
Interventions
DEVICELight exposure
The 6 lights used randomly are : * 482nm =standard blue light illumination, * 650nm, * 675nm, * 700nm, * 750nm * 800nm
Sponsors
University of Saint-Etienne
Centre Hospitalier Universitaire de Saint Etienne
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Each patient is its own control
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Social security insurance * Suspected infectious keratitis (clinically defined. No lab testing required) * Signed informed consent
Exclusion criteria
* Major Blepharospasm * Aphakia (absence of lens) * Pregnant woman * Nursing mother
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Light intensity | At the inclusion | For each wavelength, the highest light intensity tolerated by the patient is measured (mWatts/cm² ) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Severity of the keratitis | At the inclusion | It is determined by slit lamp. The result is severe or not severe |
Countries
France
Outcome results
None listed