Characterization of the Autofluorescence of Healthy and Pathological Tissues of Vocal Cords

Caractérisation de l'Autofluorescence Des Tissus Sains et Pathologiques Des Cordes Vocales

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03585075

Acronym

FLUOROCORD

Enrollment

Registered

2018-07-12

Start date

2014-02-28

Completion date

2016-04-30

Last updated

2018-07-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laryngeal Neoplasms

Brief summary

The aim of this clinical trial is to provide information about autofluorescence of pathological versus healthy vocal folds tissues. Experimentations are performed on vocal folds biopsies obtained from patients, surgered at ENT department, university hospital of Besançon. After being extracted, samples of vocal folds are submitted to excitations at 365 nm, 405 nm and 450 nm; light spectral absorptions are measured, and results are compared to reference anatomopathology.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* patient view in ENT department, presenting vocal fold lesion that necessitate biopsy * patient informed and with non opposition

Exclusion criteria

* small (\<1mm) and/or brittle sample * Patients in emergency situations, pregnant or nursing mothers, persons deprived of their liberty, minors or protected adults.

Design outcomes

Primary

Measure	Time frame
hyperspectral fluorescence of vocal folds	30 minutes after biopsy

Countries

France

Outcome results