Alveolar Bone Loss, Alveolar Bone Resorption, Bone Graft Failure
Conditions
Brief summary
Histological Measurement Comparing the density of the new bone formed during socket preservation technique using a Mixture of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture of Injectable Platelets Rich Fibers, ABB And Autogenous Particulates (sticky bone). radiographical measurements of the amount of bone dimensions changes in socket preservation technique in 6-month period using a Mixture Of Anorganic Bovine Bone(ABB) And Autogenous Particulate vs a Mixture Of Injectable Platelets Rich Fibers, ABB And Autogenous Particulates (sticky bone)
Interventions
PROCEDUREABB And Autogenous Particulate
Mixing the autogenous bone graft aquired at the time of surgery with a 50:50 ration of anorganic bovine bone and filling the socket
PROCEDUREPRF, ABB & Autogenous Particulate
adding an injectable platelets rich fibrin to a Mixture of autogenous bone graft aquired at the time of surgery with a 50:50 ration of anorganic bovine bone and filling the socket
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes
Inclusion criteria
* Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation. * Both sexes. * No intraoral soft and hard tissue pathology. * No systemic condition that contraindicate implant placement.
Exclusion criteria
* Presence of fenestrations or dehiscence of the residual bony Walls after extraction. * Heavy smokers more than 20 cigarettes per day .(24) * Patients with systemic disease that may affect normal healing. * Psychiatric problems * Disorders to implant are related to history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site. * Patients that refuse to be called back for implant placement post extraction. * Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| histomorphometrical bone quality | 6 month | histological bone quality measured from a core sample taken from the grafted site |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| marginal bone loss | 6 month | alveolar margin bone loss measured be CBCT |
Contacts
Primary ContactMohammed D Darwish, Masters
Backup ContactMohammed D Darwish, Masters
Outcome results
None listed