Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge

Alveolar Ridge Preservation in Mandibular Molars Using Mixture of Autogenous Bone & Anorganic Bovine Bone (ABB) Versus Anorganic Bovine Bone Alone Versus Absorbent Gelatin Sponge

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03584984

Enrollment

Registered

2018-07-12

Start date

2018-08-01

Completion date

2019-07-01

Last updated

2018-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alveolar Bone Loss, Alveolar Bone Resorption, Bone Graft Failure, Bone Resorption

Brief summary

Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement

Interventions

PROCEDUREMixture of Autogenous bone & Anorganic Bovine Bone (ABB)

Filling the socket with Mixing of autogenous bone graft and anorganic bovine bone in a 50:50 ratio

PROCEDUREAnorganic Bovine Bone (ABB)

Filling the socket with Anorganic bovine bone graft material only

PROCEDUREAbsorbable gelatin sponge

Filling the socket with an absorbable gelatin sponge foam pack

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation. * Both sexes. * No intraoral soft and hard tissue pathology. * No systemic condition that contraindicate implant placement.

Exclusion criteria

* Presence of fenestrations or dehiscence of the residual bony Walls after extraction. * Heavy smokers more than 20 cigarettes per day .(24) * Patients with systemic disease that may affect normal healing. * Psychiatric problems * Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site. * Patients that refuse to be called back for implant placement post extraction. * Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration. * Pregnant Females.

Design outcomes

Primary

Measure	Time frame	Description
Histomorphometrical bone analysis	6 month post primary surgery	histological bone core analysis

Secondary

Measure	Time frame	Description
Alveolar Bone marginal loss	6 month post primary surgery	CBCT measurements of marginal bone dimensional difference

Contacts

Primary ContactDina M. Al-Esawy, Masters

dr.dina.alesawy@hotmail.com01206036365

Backup ContactDina M. Al-Esawy, Masters

dr.dina.alesawy@hotmail.com01206036565

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026