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Psychosis Screening in Juvenile Justice

Reducing the Duration of Untreated Illness Among Youth in the Juvenile Justice System With Psychosis-Spectrum Disorders

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03583073
Acronym
JJ-Psychosis
Enrollment
77
Registered
2018-07-11
Start date
2018-09-01
Completion date
2023-04-30
Last updated
2024-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychosis Nos/Other, Psychotic Disorders

Keywords

psychosis, clinical high risk

Brief summary

This study will investigate the occurrence of psychosis-spectrum disorders among youth in the Juvenile Justice System and track mental health referrals for these youth in Phase 1, a standard care condition. Then, in Phase 2, an enhanced referral and linkage to care model will be employed, with the aim of bolstering motivation for and engagement in mental health treatment. It is hypothesized that the enhanced referral protocol will promote completion of mental health care referrals.

Detailed description

Among adolescents in the Juvenile Justice System (JJS), an estimated 3% have a psychotic illness, and it can be reasonably assumed that many more experience subthreshold psychotic-spectrum symptoms that may be indicative of risk. Evidence suggests that as many as 25% of those with first episode psychosis (FEP) have their first contact with care through criminal justice agencies. Duration of untreated psychosis (DUP), a negative prognostic factor, has been shown to be longer among those within the criminal justice system. This suggests that youth with psychotic symptoms who end up in the JJS may not receive appropriate mental health care. This study will first track mental health referrals for JJ youth with psychosis-spectrum symptoms in Phase 1, a standard care condition, and then an enhanced referral and linkage to care model will be investigated in Phase 2 of the study. The current study will be conducted in the Rhode Island Family Court Juvenile Intake Department where all youth receive a mental health screen (Massachusetts Youth Screening Instrument - 2nd Ed; MAYSI -2). All youth who screen positive on the MAYSI-2 Thought Disturbance scale, and a second gate screening with the Prodromal Questionnaire - Brief Version (PQ-B), will be given referral information for Coordinated Specialty Care (CSC) services by JJS staff. Enrolled families will also participate in the research assessment, regardless of whether they pursue the CSC referral, which involves the Structured Interview for Psychosis-risk Syndromes \[SIPS\] and other measures to thoroughly assess history of psychotic symptoms, comorbid difficulties, and mental health care engagement. A comparison sample of youth who screen negative on the MAYSI-2 Thought Disturbance subscale will also be assessed with the SIPS to determine accuracy of the MAYSI-2/PQ-B screen in the identification of psychosis-risk. During the first phase of the study, JJS staff will follow standard procedures in referring youth to the state CSC. In the second phase of the study, JJS will be instructed in an enhanced referral/linkage to care protocol, including a warm hand-off where referrals will be put in direct and immediate contact with CSC staff. CSC staff will also be trained in procedures to increase the likelihood of follow through with the referral to the CSC. Three month follow-up qualitative interviews and quantitative assessments regarding referral pathways, bottlenecks and gaps in care, youth psychiatric symptoms, and JJS contacts will be conducted. This design maps onto the stated goals of PAR 16- 264 including: 1) Identify baseline rates of DUP within the JJS (and the investigators will also look at rates of psychosis-spectrum symptoms and disorders); 2) Map referral pathways to CSC; 3) Identify implementation and service level factors that create bottlenecks and gaps in linkage to the CSC; 4) Investigate the relationship between treatment linkage and psychotic symptoms/DUP; and, 5) Pilot test feasible strategies for reducing DUP.

Interventions

BEHAVIORALEnhanced Referral/Linkage to Care

The JJ worker reviews with the family psychoeducation material about the role of mental health care in emotional/behavioral problems. The JJ intake worker will contact the CSC program directly with the family for a warm hand-off. The CSC worker will speak with the parent and arrange for an intake evaluation. For families already receiving treatment, the CSC referral will be for consultation. Via phone, the CSC clinician will use a motivational interviewing style to encourage families to attend the appointment. Three and seven days after referral, the JJ worker will text the caregiver to see if the CSC appointment was kept. If not, the JJ worker will text the parent the CSC phone number and also ask permission to contact the CSC to assist the family in setting up another appointment.

BEHAVIORALStandard Care

Referral to the Coordinated Specialty Care (CSC) clinic

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Brown University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)

Intervention model description

The intervention will have two phases: 1) a Standard Care (baseline control) condition, followed by, 2) an Enhanced Referral/Linkage to Care condition. Because this is a roll-out trial, the two conditions will be compared using a non-randomized open trial design.

Eligibility

Sex/Gender
ALL
Age
12 Years to 17 Years
Healthy volunteers
No

Inclusion criteria

* Adolescent being seen in the Juvenile Justice System * Legal guardian available to consent for juvenile's participation * Adolescent assents to participate * Adolescent is English speaking * Parent/guardian may be English or Spanish-speaking * Adolescent flags positive on the MAYSI-2 Thought Disturbance subscale or the PQ-B

Exclusion criteria

* Adolescent has observable developmental delays that would interfere with obtaining assent and/or accurate assessment * Adolescent meets hospital level of care for imminent risk due to severity of symptoms

Design outcomes

Primary

MeasureTime frameDescription
Number of Participants Who Used Outpatient Mental Health Services3-month follow-upNumber of Participants who Used Any Outpatient Mental Health Services by Participant's Caregiver Report

Secondary

MeasureTime frameDescription
Psychosis-spectrum Positive Symptoms3-month follow-upPsychosis-spectrum subscale of The Structured Interview for Psychosis-risk Syndromes (SIPS) has five positive symptoms including odd or delusional thoughts, paranoia/suspiciousness, grandiosity, perceptual abnormalities, and disorganized communication. Each symptom is scored on a scale from 0 to 6 and a total suscale score is calculated, ranging from 0 to 30. Higher scores indicate greater severity of positive symptoms and potentially higher risk for developing psychosis.

Countries

United States

Participant flow

Recruitment details

A total of 77 participants who screened positive for psychosis risk agreed to participate in the study.

Participants by arm

ArmCount
Standard Care/Baseline Control
Standard care is the typical process of referral to mental health services for Juvenile Justice (JJ) youth who screen positive for mental heath concerns at intake. For this study, baseline control participants will be referred to the Coordinated Specialty Care (CSC) clinic due to their endorsement of psychosis-spectrum symptoms. Standard Care: Referral to the Coordinated Specialty Care (CSC) clinic
37
Enhanced Referral/Linkage to Care
The experimental condition will include a psychoeducational and motivational enhancement protocol completed at the JJS intake appointment, paired with a warm hand-off referral to the CSC for evaluation and initiation of mental health services. Enhanced Referral/Linkage to Care: The JJ worker reviews with the family psychoeducation material about the role of mental health care in emotional/behavioral problems. The JJ intake worker will contact the CSC program directly with the family for a warm hand-off. The CSC worker will speak with the parent and arrange for an intake evaluation. For families already receiving treatment, the CSC referral will be for consultation. Via phone, the CSC clinician will use a motivational interviewing style to encourage families to attend the appointment. Three and seven days after referral, the JJ worker will text the caregiver to see if the CSC appointment was kept. If not, the JJ worker will text the parent the CSC phone number and also ask permission to contact the CSC to assist the family in setting up another appointment.
20
Total57

Withdrawals & dropouts

PeriodReasonFG000FG001
Overall StudyLost to Follow-up812

Baseline characteristics

CharacteristicEnhanced Referral/Linkage to CareTotalStandard Care/Baseline Control
Age, Categorical
<=18 years
19 Participants55 Participants36 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
1 Participants2 Participants1 Participants
Age, Continuous14.30 years
STANDARD_DEVIATION 1.56
14.60 years
STANDARD_DEVIATION 1.54
14.76 years
STANDARD_DEVIATION 1.53
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants1 Participants1 Participants
Race (NIH/OMB)
Asian
0 Participants1 Participants1 Participants
Race (NIH/OMB)
Black or African American
6 Participants19 Participants13 Participants
Race (NIH/OMB)
More than one race
2 Participants7 Participants5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants1 Participants1 Participants
Race (NIH/OMB)
White
12 Participants28 Participants16 Participants
Region of Enrollment
United States
20 Participants57 Participants37 Participants
Sex: Female, Male
Female
13 Participants31 Participants18 Participants
Sex: Female, Male
Male
7 Participants26 Participants19 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 370 / 20
other
Total, other adverse events
0 / 370 / 20
serious
Total, serious adverse events
0 / 370 / 20

Outcome results

Primary

Number of Participants Who Used Outpatient Mental Health Services

Number of Participants who Used Any Outpatient Mental Health Services by Participant's Caregiver Report

Time frame: 3-month follow-up

ArmMeasureValue (COUNT_OF_PARTICIPANTS)
Standard Care/Baseline ControlNumber of Participants Who Used Outpatient Mental Health Services20 Participants
Enhanced Referral/Linkage to CareNumber of Participants Who Used Outpatient Mental Health Services9 Participants
p-value: 0.053Chi-squared, Corrected
Secondary

Psychosis-spectrum Positive Symptoms

Psychosis-spectrum subscale of The Structured Interview for Psychosis-risk Syndromes (SIPS) has five positive symptoms including odd or delusional thoughts, paranoia/suspiciousness, grandiosity, perceptual abnormalities, and disorganized communication. Each symptom is scored on a scale from 0 to 6 and a total suscale score is calculated, ranging from 0 to 30. Higher scores indicate greater severity of positive symptoms and potentially higher risk for developing psychosis.

Time frame: 3-month follow-up

ArmMeasureValue (MEAN)Dispersion
Standard Care/Baseline ControlPsychosis-spectrum Positive Symptoms5.89 score on a scaleStandard Deviation 3.64
Enhanced Referral/Linkage to CarePsychosis-spectrum Positive Symptoms3.95 score on a scaleStandard Deviation 4.12
p-value: 0.07295% CI: [-0.18, 4.06]Chi-squared, Corrected

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026