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Scleral Hydrops and Intralabyrinthine Schwannoma

Scleral Hydrops and Intralabyrinthine Schwannoma

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03581396
Enrollment
30
Registered
2018-07-10
Start date
2018-06-22
Completion date
2019-06-30
Last updated
2018-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hydrops Saccular

Keywords

Hydrops sacculaire, schwannoma intralabyrinth

Brief summary

The symptoms of intralabyrinthine schwannomas (vertigo, deafness, instability, tinnitus) cut across the symptoms found in pressure pathologies involving the inner ear, particularly the endolymphatic hydrops. Some publications have described dilatation of the membranous labyrinth (hydrops) in the presence of intralabyrinthine tumors. It would be interesting to measure the size of the saccule (structure of the membranous labyrinth) in the presence of an intralabyrinthine schwannoma, to evaluate if some of the symptoms presented by the patients could be explained by the concomitant presence of an endolymphatic hydrops (accessible to drug therapy - Betahistine).

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age\> 18, * Subject having benefited from an exploration of internal auditory canals by MRI in our service at CHU de Hautepierre between January 1, 2008 and October 1, 2017 * Presence on the MRI of the internal auditory ducts, including the realization of a high resolution fluid sequence of FIESTA-C (exploitable) type, of an intralabyrinthine schwannoma, without extension to the internal auditory canal. * Subject who has agreed to the use of medical data for the purposes of this research. Criteria for Non Inclusion * Refusal of the patient to participate in the study * Absence of high resolution fluid sequence of fast imaging employing steady state acquisition (FIESTA-C) * Presence of movement artifacts interfering with the interpretation of the FIESTA-C sequence * Interior surgery of the inner ear or pontocerebellar angle, without preoperative imaging Inflammatory or infectious pathology of the concomitant middle or inner ear * Extension of schwannoma to the internal auditory canal * Impossibility of giving the subject informed information (difficulty understanding the subject,) * Subject under the protection of justice * Subject under guardianship or curatorship

Design outcomes

Primary

MeasureTime frameDescription
Size of intralabyrinth saccules1 hour after the realization of the MRI]To measure saccule size (membranous labyrinth structure) in patients with intralabyrinthine schwannoma on a high resolution fluid sequence (FIESTA-C) in 3T MRI

Countries

France

Contacts

Primary ContactAïna VENKATASAMY,, MD
aina.venkatasamy@chru-strasbourg.fr33 3 88 12 78 65

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026