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CODP Imaging From a Dose Perspective

CODP Imaging From a Dose Perspective - Effective Organ Doses of a Combined Inspiration-expiration Protocol on a 3rd Generation Dual-source CT

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03581110
Enrollment
1957
Registered
2018-07-10
Start date
2014-08-31
Completion date
2017-09-30
Last updated
2018-07-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Radiation

Keywords

COPD, Computed tomography, Expiration, organ specific radiation dose

Brief summary

The noncontrast-enhanced chest computed tomography (CT) is an emerging diagnostical tool in patient with chronic obstructive pulmonary disease (COPD). As shown in previous studies and pointed out by the Fleischner society, an additional scan in expiration reflects the pathophysiology of this complex disease better and extends the clinical information of the CT. Nevertheless, this scan is leading to an increase in radiation dose. But currently it is unclear if this increased radiation dose is proportional to the additional clinical value when compared to inspiration-only protocols. Therefore, the aim of this study was to compare the organ specific radiation doses of a combined inspiration-expiration CT on a 3rd generation dual-source scanner with noncontrast-enhanced chest CTs of two clinical routine scanners. Therefore, the radiation doses of nearly 2000 chest CTs have been evaluated.

Interventions

DIAGNOSTIC_TESTcomputed tomography

noncontrast-enhanced chest computed tomography

Sponsors

Universitätsmedizin Mannheim
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* noncontrast-enhanced chest CT performed on one of the named devices * imaging performed between August 2014 and September 2017 * CT protocol used as previously specified

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
organ specific radiation dosesThe organ dose calculations have been performed retrospectively. Therefore, the time frame is variable. The time set for the final outcome calculations was September 2017. Therefore, the time frame varies between 3 years and 1 week.Organ specific radiation doses of 17 individual organs

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026