Ridge Preservation Comparing Simultaneous vs. Delayed Grafting

Ridge Preservation Comparing the Traditional Approach vs. Early Implant Placement With Simultaneous Contour Augmentation

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03580798

Enrollment

Registered

2018-07-09

Start date

2018-11-08

Completion date

2019-04-26

Last updated

2020-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Loss

Brief summary

Comparison of the clinical healing of simultaneous vs. delayed grafting for dental implant placement.

Detailed description

The primary aims of this study are to compare the clinical and histologic results of a traditional ridge preservation with implant placement at 16 weeks (control group) with early implant placement (8 weeks) with simultaneous contour augmentation as described by Buser (test group).

Interventions

PROCEDUREDelayed graft

8 weeks post-extraction 15 test patients will receive implant placement plus osseous grafting.

PROCEDURESimultaneous graft

At the time of extraction osseous graft will be placed in the socket and implant placed 4 months later.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Have one non-molar maxillary tooth requiring extraction that will be replaced by a dental implant. The site must be bordered by 2 teeth. * Healthy persons at least 18 years old. * Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.

Exclusion criteria

* Patients with debilitating systemic disease, or diseases that have a clinically significant effect on the periodontium. * Exclude any molar tooth. * Presence of or history of osteonecrosis of jaws. * Patients with current or previous history of IV bisphosphonates, irrespective of duration. * Patients taking oral bisphosphonates for ≥ 3 years. * Pregnant women. * Allergy to any material or medication used in the study. * Patients who need prophylactic antibiotics prior to dental procedures. * Previous head and neck radiation therapy. * Chemotherapy in the previous 12 months.

Design outcomes

Primary

Measure	Time frame	Description
Final ridge width for simultaneous and delayed grafting treatment.	16 to 20 weeks	Measure final ridge width to determine if adequate bone is available.

Secondary

Measure	Time frame	Description
Soft tissue thickness	16 to 20 weeks	Facial and occlusal
Histology	16 weeks	Histologic composition for control group only
Implant dehiscence	20 weeks	Implant dehiscence

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026