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Chronic Obstructive Pulmonary Disease

The Effect of Adding Neuromuscular Electrical Stimulation to Endurance and Resistance Training on Exercise Capacity and Balance in Patients With Chronic Obstructive Pulmonary Disease: a Randomized Clinical Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03577080
Acronym
COPD
Enrollment
42
Registered
2018-07-05
Start date
2016-10-28
Completion date
2017-06-10
Last updated
2019-09-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

COPD

Keywords

COPD, Exercise training

Brief summary

Chronic Obstructive Pulmonary Disease (COPD) is a preventable respiratory characterized by airflow obstruction that is not fully reversible. This disease a major cause of mortality worldwide. It is projected to rank the third-leading cause of death in 2020. The objective of this study is to examine the effects of a physical therapy intervention in stable patients with COPD.

Detailed description

Chronic obstructive pulmonary disease (COPD) patients have demonstrated important balance impairment (1).The deficit in balance control is identified as one of the risk factors of fall in subjects with COPD and alters their activities daily life (2,3). Porto and al. (2015) reported in a recent review that individuals with COPD have a decline in balance control when compared with healthy age matched controls(4).

Interventions

OTHERET+RT+ NMES

Endurance training, resistance training and neuromuscular electrical stimuation were prformed. Intensity was gradually increased.

Sponsors

Faculty of Medicine, Sousse
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Caregiver, Investigator)

Intervention model description

Differents groups received differents training protocoles during the same duration

Eligibility

Sex/Gender
MALE
Age
40 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

* COPD diagnosed by pulmonary function testing * Clinically stable * Abscence of other obstructive diseases * Signed written consent * Fall in the past five years or recent near fall

Exclusion criteria

* Neuromuscular diseases * Severe psychiatric, neurologic or musculoskeletal conditions and /or instable cardiovascular diseases. * Contre-indications to physical therapy * Acute exacerbations a month before the intervention

Design outcomes

Primary

MeasureTime frameDescription
Balance outcomesbaselineThe tests were performed using a stabilometric platform

Secondary

MeasureTime frameDescription
Pulmonary function testbaselineThe test was performed using a Spirometry Zan 100 (Inspire Health GmbH, Germany)
Exercise tolerancebaselineThe 6 minutes walk test
Force assesmentBasellineMaximal voluntary contraction (MVC) of the quadriceps muscle
Time Up and Go (TUG)BaselineThe patient initially sitting on an armless chair stand up walks 3 meters and returns and sit down again. The time was recorded
Berg Balance Scale (BBS)BaselineThe BBS contains 14 items. The score obtained from 0 to 56. from 0 to 20: high risk of falling , Above 56: No risk of falling

Countries

Tunisia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026