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Multiparametric Diagnostic Model of Thick-section Clinical-quality MRI Data in Detecting Migraine Without Aura

Multiparametric Diagnostic Model of Thick-section Clinical-quality MRI Data in Detecting Migraine Without Aura

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03570086
Enrollment
400
Registered
2018-06-26
Start date
2018-07-01
Completion date
2019-12-30
Last updated
2018-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine Without Aura

Brief summary

Recently, radiomics combined with machine learning method has been widely used in clinical practice. Compared with traditional imaging studies that explore the underlying mechanisms, the machine learning method focuses on classification and prediction to propose personalized diagnosis and treatment strategies. However, these studies were based on thin-section research-quality brain MR imaging with section thickness of \< 2 mm. Clinical, the usage of thick-section clinical setting instead of thin-section research setting is especially important to shorten the acquisition time to reduce the patient's suffering. Here investigators want to build multiparametric diagnostic model of migraineurs without aura using radiomics features extracted from thick-section clinical-quality brain MR images.

Interventions

DIAGNOSTIC_TESTdiagnostic

using radiomics features from multiparametric thick-section clinical-quality brain MRI to distinguish migraineurs from health controls.

Sponsors

Xidian University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
21 Years to 55 Years
Healthy volunteers
Yes

Inclusion criteria

* right-handed * International Headache Society criteria for episodic migraine without aura

Exclusion criteria

* addition (including alcohol, nicotine, or drug) * physical illness

Design outcomes

Primary

MeasureTime frameDescription
accuracy2018.7-2019.12a measure of statistical bias which measures the proportion of health controls and migrainures that are correctly identified as such.
sensitivity2018.7-2019.12true positive rate of detection in migraineurs which measures the proportion of actual migraineurs that are correctly identified as such.
specificity2018.7-2019.12true negative rate measures the proportion of actual health controls that are correctly identified as such.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026